(Q54379965)

29 May 2018

title

High dose methotrexate therapy: insecure rationale? (English)

1 reference

29 May 2018

High dose methotrexate therapy: Insecure rationale? (English)

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

5 January 2023

1 reference

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

5 January 2023

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

5 January 2023

author name string

B. A. Kamen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3395351

5 January 2023

N. J. Winick

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3395351

5 January 2023

language of work or name

English

0 references

publication date

1 July 1988

1 reference

29 May 2018

15 July 1988

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=3395351

full work available at URL

5 January 2023

https://api.elsevier.com/content/article/PII:0006295288900329?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

https://api.elsevier.com/content/article/PII:0006295288900329?httpAccept=text/plain

5 January 2023

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

5 January 2023

published in

Biochemical Pharmacology

1 reference

29 May 2018

volume

37

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29 May 2018

issue

14

1 reference

29 May 2018

page(s)

2713-2715

1 reference

29 May 2018

Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid

cites work

1

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Favorable response of metastatic osteogenic sarcoma to pulse high-dose methotrexate with citrovorum rescue and radiation therapy

5 January 2023

4

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

A randomized comparison of high-dose infusion methotrexate versus standard-dose weekly therapy in head and neck squamous cancer

5 January 2023

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1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen

5 January 2023

7

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Detection by high-performance liquid chromatography of methotrexate and its metabolites in tumor tissue from osteosarcoma patients treated with high-dose methotrexate/leucovorin rescue

5 January 2023

8

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Methotrexate (MTX) concentration in tumors following low-dose MTX

5 January 2023

9

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Methotrexate resistance and gene amplification. Mechanisms and implications

5 January 2023

12

1 reference

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Lack of dihydrofolate reductase in human tumor and leukemia cells in vivo

5 January 2023

13

1 reference

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Heterogeneity in the specific activity and methotrexate sensitivity of dihydrofolate reductase from blast cells of acute myelogenous leukemia patients.

5 January 2023

14

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma

5 January 2023

16

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Gene amplification in a leukemic patient treated with methotrexate

5 January 2023

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1 reference

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Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates

5 January 2023

18

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

5 January 2023

19

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Methotrexate and folate content of erythrocytes in patients receiving oral vs intramuscular therapy with methotrexate

5 January 2023

20

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates

5 January 2023

21

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Folate and methotrexate polyglutamate tissue levels in rhesus monkeys following chronic low-dose methotrexate.

5 January 2023

23

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Folate-dependent enzymes in cultured Chinese hamster cells: Folylpolyglutamate synthetase and its absence in mutants auxotrophic for glycine + adenosine + thymidine

5 January 2023

24

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Characteristics of methotrexate polyglutamate formation in cultured hepatic cells

5 January 2023

26

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Regulation of methotrexate polyglutamate accumulation in vitro: effects of cellular folate content

5 January 2023

28

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Continuous infusion of methotrexate in children with acute leukemia

5 January 2023

31

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

Receptor-mediated folate accumulation is regulated by the cellular folate content

5 January 2023

33

1 reference

https://api.crossref.org/works/10.1016/0006-2952(88)90032-9

5 January 2023

Identifiers

1 reference

29 May 2018

1 reference

29 May 2018