(Q54383379)

29 May 2018

title

Methotrexate-resistant Leishmania donovani genetically deficient in the folate-methotrexate transporter (English)

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

1 reference

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

Leishmania donovani

object named as

Leishmania donovani

1 reference

K. Kaur

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3366764

2 January 2023

T. Coons

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3366764

2 January 2023

K. Emmett

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3366764

2 January 2023

B. Ullman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3366764

2 January 2023

language of work or name

English

0 references

publication date

1 May 1988

1 reference

29 May 2018

25 May 1988

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=3366764

full work available at URL

2 January 2023

http://intl.jbc.org/cgi/content/abstract/263/15/7020

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3366764

https://api.elsevier.com/content/article/PII:S0021925818685989?httpAccept=text/xml

2 January 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

https://api.elsevier.com/content/article/PII:S0021925818685989?httpAccept=text/plain

2 January 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Journal of Biological Chemistry

2 January 2023

published in

1 reference

29 May 2018

volume

263

1 reference

29 May 2018

issue

15

1 reference

29 May 2018

page(s)

7020-7028

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29 May 2018

The chemotherapy of trypanosome infections

cites work

2

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Ciba Foundation Symposium

2 January 2023

3

20

309

Peters

1974

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

The problem of drug resistance in malaria

2 January 2023

5

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

2 January 2023

7

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells

2 January 2023

8

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Detective transport of amethopterin (methotrexate) as a mechanism of resistance to the antimetabolite in L5178Y leukemic cells

2 January 2023

9

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

10

28

75

Sirotnak

1968

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

11

41

4447

Sirotnak

1981

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Purification and properties of dihydrofolate reductase from methotrexate-sensitive and methotrexate-resistant Chinese hamster ovary cells

2 January 2023

12

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate

2 January 2023

13

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Acquired methotrexate resistance in lymphoblasts resulting from altered kinetic properties of dihydrofoltate reductase

2 January 2023

14

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Increased levels of folic acid reductase as a mechanism of resistance to amethopterin in leukemic cells.

2 January 2023

15

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Hybridization of hamster cells with high and low folate reductase activity

2 January 2023

16

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Gene amplification in cultured animal cells

2 January 2023

19

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica

2 January 2023

20

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Dihydrofolate reductase: thymidylate synthase, a bifunctional polypeptide from Crithidia fasciculata

2 January 2023

21

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa

2 January 2023

22

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization.

2 January 2023

23

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Impaired drug uptake in methotrexate resistant Crithidia fasciculata without changes in dihydrofolate reductase activity or gene amplification

2 January 2023

25

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Studies on the interaction of tritium-labeled aminopterin with dihydrofolic reductase

2 January 2023

27

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium

2 January 2023

28

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Two high affinity nucleoside transporters in Leishmania donovani

2 January 2023

30

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

2 January 2023

31

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Effect of substrate decomposition on the spectrophotometric assay of dihydrofolate reductase

2 January 2023

32

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Purification and characterization of the bifunctional thymidylate synthetase-dihydrofolate reductase from methotrexate-resistant Leishmania tropica.

2 January 2023

33

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Structure of mRNA encoded by tubulin genes in Leishmania enriettii.

2 January 2023

35

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

Molecular Pharmacology

37

5

49

Ferone

1969

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Effects of trimethoprim on folate metabolism in man

2 January 2023

39

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine.

2 January 2023

41

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Genetic and biochemical characterization of multidrug resistance

2 January 2023

44

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

45

45

3002

Fojo

1985

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

The sulfonamides

47

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

The sulfonamides

48

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

The sulfonamides

49

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

In vitro activity of sulfonamides and sulfones against Leishmania major promastigotes

2 January 2023

50

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

52

41

3621

Mordoh

1981

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Structural requirements for anion substrates of the methotrexate transport system in L1210 cells

2 January 2023

53

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Characteristics of folic acid transport in the L1210 leukemia cell

2 January 2023

54

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

A model system for the study of heteroexchange diffusion: Methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells

2 January 2023

55

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

56

46

1639

Henderson

1986

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

57

32

1416

Nahas

1972

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

59

45

3992

Sirotnak

1985

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

The growth and nutrition of Crithidia fasciculata

2 January 2023

60

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Pteridine Requirement of the HemoflagellateLeishmania tarentolae

2 January 2023

61

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Folate utilisation by Leishmania species and the identification of intracellular derivatives and folate-metabolising enzymes

2 January 2023

63

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Effects of long-chain mono- and dicarboxylic acids on the pteridine requirement of Crithidia

2 January 2023

65

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Methionine or Folate and Phosphoenolpyruvate in the Biosynthesis of Threonine inCrithidia fasciculata1

2 January 2023

66

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

Pteridine-requiring dihydroorotate hydroxylase from Crithidiafasciculata

2 January 2023

67

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)68598-9

2 January 2023

Identifiers

1 reference

29 May 2018