(Q54383542)

29 May 2018

title

RIPK3 as a potential therapeutic target for Gaucher's disease. (English)

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29 May 2018

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7

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29 May 2018

Anthony H. Futerman

9

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29 May 2018

ANDRES KLEIN

object named as

Andrés D Klein

6

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Einat. B. Vitner

object named as

Einat B Vitner

1

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author name string

Ran Salomon

2

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29 May 2018

Tamar Farfel-Becker

3

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29 May 2018

Anna Meshcheriakova

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29 May 2018

Mohammad Ali

5

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29 May 2018

Timothy M Cox

8

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29 May 2018

language of work or name

English

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publication date

19 January 2014

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29 May 2018

published in

Nature Medicine

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29 May 2018

volume

20

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29 May 2018

issue

2

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29 May 2018

page(s)

204-208

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29 May 2018

https://scigraph.springernature.com/pub.10.1038/nm.3449

exact match

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cites work

The cell biology of lysosomal storage disorders

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Neuropathology provides clues to the pathophysiology of Gaucher disease

21 January 2018

1 reference

Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.

21 January 2018

1 reference

Murine models of acute neuronopathic Gaucher disease

21 January 2018

1 reference

21 January 2018

1 reference

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

1 reference

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

21 January 2018

1 reference

Virus inhibition of RIP3-dependent necrosis

21 January 2018

1 reference

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

1 reference

21 January 2018

The FLIP Side of Life

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

21 January 2018

1 reference

A role of RIP3-mediated macrophage necrosis in atherosclerosis development.

21 January 2018

1 reference

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

1 reference

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

21 January 2018

1 reference

Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

21 January 2018

1 reference

Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

21 January 2018

1 reference

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

21 January 2018

1 reference

Dynamic expression of epidermal caspase 8 simulates a wound healing response

21 January 2018

1 reference

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

1 reference

Nucleocytoplasmic shuttling of receptor-interacting protein 3 (RIP3): identification of novel nuclear export and import signals in RIP3.

21 January 2018

1 reference

Murine model of genetic demyelinating disease: the twitcher mouse

21 January 2018

1 reference

Common and uncommon pathogenic cascades in lysosomal storage diseases

21 January 2018

1 reference

Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses

21 January 2018

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

21 January 2018

1 reference

Animal models for Gaucher disease research

21 January 2018

1 reference

Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia

21 January 2018

1 reference

Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

21 January 2018

1 reference

Structure-activity relationship study of tricyclic necroptosis inhibitors

21 January 2018

1 reference

Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

21 January 2018

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

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No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease.

21 January 2018

1 reference

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

21 January 2018

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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

21 January 2018

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Anatomically defined neuron-based rescue of neurodegenerative Niemann-Pick type C disorder.

21 January 2018

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Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6.

21 January 2018

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Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

21 January 2018

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β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells

21 January 2018

1 reference

Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid beta-galactosidase

21 January 2018

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12 December 2020

Competing for the treasure in exceptions

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12 December 2020

'Necrosome'-induced inflammation: must cells die for it?

1 reference

12 December 2020

A genetic storage disorder in BALB/C mice with a metabolic block in esterification of exogenous cholesterol

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12 December 2020

Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease

1 reference

12 December 2020

The glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

1 reference

12 December 2020

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3449

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29 May 2018

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29 May 2018