(Q54457075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16931516%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase (English)

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29 December 2019

1

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29 December 2019

Tracy G. Anthony

12

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29 December 2019

author name string

L Morgan Oberle

2

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29 December 2019

Sheree A Wek

3

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29 December 2019

Piyawan Bunpo

4

1 reference

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29 December 2019

Xue Ping Wang

5

1 reference

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29 December 2019

Izolda Mileva

6

1 reference

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29 December 2019

Leslie O Goodwin

7

1 reference

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29 December 2019

Carla J Aldrich

8

1 reference

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29 December 2019

Donald L Durden

9

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29 December 2019

Margaret A McNurlan

10

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29 December 2019

Ronald C Wek

11

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29 December 2019

language of work or name

English

0 references

publication date

24 August 2006

1 reference

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Journal of Biological Chemistry

29 December 2019

published in

1 reference

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29 December 2019

volume

281

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29 December 2019

issue

42

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29 December 2019

page(s)

31222-31233

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Treatment of acute lymphoblastic leukemia

29 December 2019

cites work

1 reference

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Pancreatic endocrine function in leukemic children treated with L-asparaginase

21 January 2018

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Thrombotic effects of asparaginase in two acute lymphoblastic leukemia protocols (NOPHO ALL-1992 versus NOPHO ALL-2000): a single-institution study.

21 January 2018

1 reference

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Asparaginase-induced derangements of glutamine metabolism: the pathogenetic basis for some drug-related side-effects.

21 January 2018

1 reference

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L-asparaginase effects on inhibition of protein synthesis and lowering of the glutamine content in cultured rat hepatocytes

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Regulation of asparagine synthetase gene expression by amino acid starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Glutamine deprivation induces the expression of GADD45 and GADD153 primarily by mRNA stabilization

21 January 2018

1 reference

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Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia

21 January 2018

1 reference

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Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Measurement of hepatic protein synthesis in unrestrained mice-evaluation of the 'flooding technique'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Responsiveness of muscle protein synthesis to growth hormone administration in HIV-infected individuals declines with severity of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

The best way to use asparaginase in childhood acute lymphatic leukaemia--still to be defined?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Asparagine synthetase chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Amino acid limitation regulates CHOP expression through a specific pathway independent of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Fat and protein metabolism in growing steers fed either grass silage or dried grass

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Glutamine and glutamate--their central role in cell metabolism and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase

21 January 2018

1 reference

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Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

The unfolded protein response: a stress signaling pathway critical for health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

21 January 2018

1 reference

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Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

21 January 2018

1 reference

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Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Amino acids as regulators of gene expression: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Amino Acid Limitation Induces Expression ofCHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

Mammalian target of rapamycin inhibition as therapy for hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604511200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604511200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16931516%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference