(Q54491373)

30 May 2018

title

Neuregulin-1 suppresses cardiomyocyte apoptosis by activating PI3K/Akt and inhibiting mitochondrial permeability transition pore. (English)

1 reference

30 May 2018

author name string

Bingzhang Jie

1

1 reference

30 May 2018

Xiaoxia Zhang

2

1 reference

30 May 2018

Xuesi Wu

3

1 reference

30 May 2018

Yi Xin

4

1 reference

30 May 2018

Yong Liu

5

1 reference

30 May 2018

Yongfang Guo

6

1 reference

30 May 2018

publication date

14 August 2012

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30 May 2018

Molecular and Cellular Biochemistry

published in

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30 May 2018

volume

370

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30 May 2018

issue

1-2

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30 May 2018

page(s)

35-43

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30 May 2018

https://scigraph.springernature.com/pub.10.1007/s11010-012-1395-7

exact match

0 references

cites work

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Endothelium-derived neuregulin protects the heart against ischemic injury

21 January 2018

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PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning

21 January 2018

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Phosphorylation of GSK-3β mediates intralipid-induced cardioprotection against ischemia/reperfusion injury

21 January 2018

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Relaxin antagonizes hypertrophy and apoptosis in neonatal rat cardiomyocytes.

21 January 2018

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The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.

21 January 2018

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Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway

21 January 2018

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Unique mode of cell death in freshly isolated adult rat ventricular cardiomyocytes exposed to hydrogen peroxide.

21 January 2018

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Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure.

21 January 2018

1 reference

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Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

21 January 2018

1 reference

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IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis

21 January 2018

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ErbB4 signals Neuregulin1-stimulated cell proliferation and c-fos gene expression through phosphorylation of serum response factor by mitogen-activated protein kinase cascade

21 January 2018

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Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts.

21 January 2018

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Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling

21 January 2018

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Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway

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Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes

21 January 2018

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21 January 2018

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Ischemic preconditioning requires opening of pannexin-1/P2X(7) channels not only during preconditioning but again after index ischemia at full reperfusion

21 January 2018

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21 January 2018

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Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses

21 January 2018

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21 January 2018

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Intersectin-1s Regulates the Mitochondrial Apoptotic Pathway in Endothelial Cells

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Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11010-012-1395-7

1 reference

30 May 2018

PubMed ID

22886427

1 reference

30 May 2018