(Q54517310)

30 May 2018

title

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. (English)

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30 May 2018

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8

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30 May 2018

Aurélien Roux

object named as

Aurélien Roux

6

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Howard Riezman

object named as

Howard Riezman

5

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author name string

Doris Berchtold

1

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30 May 2018

Manuele Piccolis

2

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30 May 2018

Nicolas Chiaruttini

3

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30 May 2018

Isabelle Riezman

4

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30 May 2018

Tobias C Walther

7

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30 May 2018

publication date

15 April 2012

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30 May 2018

published in

Nature Cell Biology

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30 May 2018

volume

14

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issue

5

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30 May 2018

page(s)

542-547

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30 May 2018

https://scigraph.springernature.com/pub.10.1038/ncb2480

exact match

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cites work

TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain

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Regulation of ceramide biosynthesis by TOR complex 2.

21 January 2018

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Lipid rafts: elusive or illusive?

21 January 2018

1 reference

Membrane properties of sphingomyelins

21 January 2018

1 reference

Orm family proteins mediate sphingolipid homeostasis

21 January 2018

1 reference

Target of rapamycin (TOR) in nutrient signaling and growth control

21 January 2018

1 reference

Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling

21 January 2018

1 reference

Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology

21 January 2018

1 reference

Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast

21 January 2018

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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

21 January 2018

1 reference

Caffeine extends yeast lifespan by targeting TORC1.

21 January 2018

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A protein kinase network regulates the function of aminophospholipid flippases

21 January 2018

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The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2.

21 January 2018

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Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.

21 January 2018

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The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation

21 January 2018

1 reference

The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.

21 January 2018

1 reference

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

21 January 2018

1 reference

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae

21 January 2018

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Eisosomes mark static sites of endocytosis.

21 January 2018

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Plasma membrane microdomains regulate turnover of transport proteins in yeast

21 January 2018

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Visualization of protein compartmentation within the plasma membrane of living yeast cells.

21 January 2018

1 reference

A chemical switch for inhibitor-sensitive alleles of any protein kinase

21 January 2018

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The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes

21 January 2018

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Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

21 January 2018

1 reference

Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

21 January 2018

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A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling

21 January 2018

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Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor

21 January 2018

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Cells respond to mechanical stress by rapid disassembly of caveolae

21 January 2018

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Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo

21 January 2018

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Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels

21 January 2018

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Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells

21 January 2018

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A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NCB2480

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30 May 2018

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30 May 2018