(Q54519466)

30 May 2018

title

Increased interaction between PACT molecules in response to stress signals is required for PKR activation. (English)

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30 May 2018

author name string

Madhurima Singh

series ordinal

1

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30 May 2018

Rekha C Patel

series ordinal

2

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30 May 2018

publication date

1 August 2012

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30 May 2018

Journal of Cellular Biochemistry

published in

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30 May 2018

volume

113

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30 May 2018

issue

8

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30 May 2018

page(s)

2754-2764

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30 May 2018

Analysis of monomeric and dimeric phosphorylated forms of protein kinase R.

cites work

1 reference

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

21 January 2018

1 reference

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

21 January 2018

1 reference

Alpha-interferon and its effects on signalling pathways within cells

21 January 2018

1 reference

Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways.

21 January 2018

1 reference

The double-stranded RNA-binding motif, a versatile macromolecular docking platform

21 January 2018

1 reference

Activation of PKR: an open and shut case?

21 January 2018

1 reference

A new double-stranded RNA-binding protein that interacts with PKR

21 January 2018

1 reference

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

21 January 2018

1 reference

Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression

21 January 2018

1 reference

TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress

21 January 2018

1 reference

Characterization of the TRBP domain required for dicer interaction and function in RNA interference

21 January 2018

1 reference

Effects of interferons α/β on the proliferation of human micro- and macrovascular endothelial cells

21 January 2018

1 reference

Antiviral action of the tumor suppressor ARF

21 January 2018

1 reference

Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

21 January 2018

1 reference

RNA dimerization promotes PKR dimerization and activation

21 January 2018

1 reference

Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana.

21 January 2018

1 reference

Oligomerization activity of a double-stranded RNA-binding domain

21 January 2018

1 reference

The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)

21 January 2018

1 reference

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

21 January 2018

1 reference

Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

21 January 2018

1 reference

Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity

21 January 2018

1 reference

Mechanism of PKR activation: dimerization and kinase activation in the absence of double-stranded RNA.

21 January 2018

1 reference

Mechanism of PKR Activation by dsRNA.

21 January 2018

1 reference

Molecular basis for PKR activation by PACT or dsRNA

21 January 2018

1 reference

Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

21 January 2018

1 reference

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

21 January 2018

1 reference

Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR

21 January 2018

1 reference

A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

21 January 2018

1 reference

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

21 January 2018

1 reference

Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling

21 January 2018

1 reference

PACT, a protein activator of the interferon-induced protein kinase, PKR.

21 January 2018

1 reference

Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast

21 January 2018

1 reference

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

21 January 2018

1 reference

PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR.

21 January 2018

1 reference

Modular structure of PACT: distinct domains for binding and activating PKR

21 January 2018

1 reference

Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis

21 January 2018

1 reference

Biochemical analysis of PKR activation by PACT.

21 January 2018

1 reference

Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain

21 January 2018

1 reference

The regulation of the protein kinase PKR by RNA.

21 January 2018

1 reference

Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation

21 January 2018

1 reference

Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis

21 January 2018

1 reference

A conserved double-stranded RNA-binding domain

21 January 2018

1 reference

PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

21 January 2018

1 reference

Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha).

21 January 2018

1 reference

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.

21 January 2018

1 reference

Signal integration via PKR.

21 January 2018

1 reference

Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

21 January 2018

1 reference

The role of the dsRNA-activated kinase, PKR, in signal transduction

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCB.24152

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30 May 2018

release_47svwlsxozhptb7z4nbvt66eje

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/47svwlsxozhptb7z4nbvt66eje

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

30 May 2018