(Q54519761)

30 May 2018

title

Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes. (English)

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7

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Joan K. Heath

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author name string

Jürgen Büning

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Dorthe von Smolinski

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Kianush Tafazzoli

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Klaus-Peter Zimmer

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Stephan Strobel

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Maria Apostolaki

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Diether Ludwig

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Andreas Gebert

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publication date

1 December 2008

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30 May 2018

published in

Immunology

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volume

125

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issue

4

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page(s)

510-521

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30 May 2018

Human small intestinal epithelial cells constitutively express the key elements for antigen processing and the production of exosomes

cites work

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12 December 2020

Interferon-γ mediates antigen trafficking to MHC class II-positive late endosomes of enterocytes

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12 December 2020

MHC class II compartment subtypes: structure and function

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12 December 2020

Antigen targeting to MHC class II-enriched late endosomes in colonic epithelial cells: trafficking of luminal antigens studied in vivo in Crohn's colitis patients

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12 December 2020

Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

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12 December 2020

Intestinal epithelial antigen induces CD4+ T cells with regulatory phenotype in a transgenic autoimmune mouse model

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12 December 2020

T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells

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12 December 2020

Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma

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12 December 2020

Luminal antigens access late endosomes of intestinal epithelial cells enriched in MHC I and MHC II molecules: in vivo study in Crohn's ileitis

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12 December 2020

Modulation of antigen trafficking to MHC class II-positive late endosomes of enterocytes

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12 December 2020

Antigen processing and presentation by intestinal epithelial cells - polarity and complexity

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12 December 2020

Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells.

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12 December 2020

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device

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12 December 2020

"Tolerosomes" are produced by intestinal epithelial cells

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12 December 2020

Intestinal epithelial exosomes carry MHC class II/peptides able to inform the immune system in mice

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12 December 2020

Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease

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12 December 2020

A rapid method for assessing the distribution of gold labeling on thin sections.

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12 December 2020

Distribution of class II major histocompatibility antigens in enterocytes of the rat jejunum and their association with organelles of the endocytic pathway.

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12 December 2020

Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease

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12 December 2020

Unexpected lack of reactivity of allogeneic anti-Ia monoclonal antibodies with MHC class II molecules expressed by mouse intestinal epithelial cells

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12 December 2020

Co-localization of class II antigen and exogenous antigen in the rat enterocyte

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12 December 2020

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

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12 December 2020

B lymphocytes secrete antigen-presenting vesicles

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12 December 2020

Selective modulation of the major histocompatibility complex class II antigen presentation pathway following B cell receptor ligation and protein kinase C activation

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12 December 2020

Capture and processing of exogenous antigens for presentation on MHC molecules.

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12 December 2020

Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing

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12 December 2020

Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease

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12 December 2020

The role of endosomes and lysosomes in MHC class II functioning

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12 December 2020

Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells

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12 December 2020

Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10

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12 December 2020

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

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12 December 2020

Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor alpha

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12 December 2020

Tolerosome-induced oral tolerance is MHC dependent

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12 December 2020

10.1111/J.1365-2567.2008.02864.X

Identifiers

DOI

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30 May 2018

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30 May 2018