(Q54537231)

31 May 2018

title

Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphorylation of phospho-Tyr705 largely through TC45. (English)

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31 May 2018

author name string

Ryohei Wakahara

1

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31 May 2018

Hiroyuki Kunimoto

2

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31 May 2018

Kanae Tanino

3

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31 May 2018

Hirotada Kojima

4

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31 May 2018

Akira Inoue

5

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31 May 2018

Haruo Shintaku

6

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31 May 2018

Koichi Nakajima

7

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31 May 2018

publication date

11 January 2012

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31 May 2018

published in

Genes to Cells

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31 May 2018

volume

17

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31 May 2018

issue

2

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31 May 2018

page(s)

132-145

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31 May 2018

The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway

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STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

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STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

21 January 2018

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21 January 2018

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Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

21 January 2018

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21 January 2018

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Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

21 January 2018

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Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis

21 January 2018

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Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation

21 January 2018

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STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

21 January 2018

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Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

21 January 2018

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SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

21 January 2018

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21 January 2018

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21 January 2018

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STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.

21 January 2018

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A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation

21 January 2018

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

21 January 2018

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STAT3 inhibition of gluconeogenesis is downregulated by SirT1

21 January 2018

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Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

21 January 2018

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STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen

21 January 2018

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Physical and functional interactions between STAT3 and ZIP kinase

21 January 2018

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Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation.

21 January 2018

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Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation

21 January 2018

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Phosphorylation of STAT3 serine-727 by cyclin-dependent kinase 1 is critical for nocodazole-induced mitotic arrest.

21 January 2018

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The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

21 January 2018

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Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

21 January 2018

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Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling

21 January 2018

1 reference

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The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

21 January 2018

1 reference

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Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

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Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

21 January 2018

1 reference

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Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

21 January 2018

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SOCS proteins, cytokine signalling and immune regulation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

21 January 2018

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Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

Region 752-761 of STAT3 is critical for SRC-1 recruitment and Ser727 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2011.01575.X

10.1111/J.1365-2443.2011.01575.X

21 January 2018

Identifiers

DOI

1 reference

31 May 2018

PubMed ID

22233524

1 reference

31 May 2018