(Q54538313)

31 May 2018

title

Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. (English)

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31 May 2018

author

Owen J Sansom

10

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31 May 2018

Alan R. Clarke

12

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31 May 2018

John O Mason

John O Mason

11

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Hans Clevers

8

Hans Clevers

1 reference

31 May 2018

Valerie S Meniel

3

Valerie Meniel

1 reference

31 May 2018

Trevor Hay

2

Trevor Hay

1 reference

31 May 2018

author name string

Ronald C J Gallagher

1

1 reference

31 May 2018

Catherine Naughton

4

1 reference

31 May 2018

Thomas J Anderson

5

1 reference

31 May 2018

Hiroyuki Shibata

6

1 reference

31 May 2018

Masaki Ito

7

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31 May 2018

Tetsuo Noda

9

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31 May 2018

language of work or name

English

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publication date

1 September 2002

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31 May 2018

published in

Oncogene

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31 May 2018

volume

21

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31 May 2018

issue

42

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31 May 2018

page(s)

6446-6457

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31 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205892

exact match

0 references

cites work

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Wnt-4 expression induces a pregnancy-like growth pattern in reconstituted mammary glands in virgin mice.

21 January 2018

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A paracrine role for the epithelial progesterone receptor in mammary gland development

21 January 2018

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Wnt signaling: a common theme in animal development

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The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

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MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways

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Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

21 January 2018

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21 January 2018

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Somatic mutations of the APC gene in primary breast cancers

21 January 2018

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Identification and characterization of the familial adenomatous polyposis coli gene

21 January 2018

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

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Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland

21 January 2018

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The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

21 January 2018

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Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers

21 January 2018

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Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice

21 January 2018

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Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

21 January 2018

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APC expression in normal human tissues

21 January 2018

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Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

21 January 2018

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ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias

21 January 2018

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The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

21 January 2018

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Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

21 January 2018

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Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis

21 January 2018

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The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

21 January 2018

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Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

21 January 2018

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Efficient BLG-Cre mediated gene deletion in the mammary gland.

21 January 2018

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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21 January 2018

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Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

21 January 2018

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Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

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Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

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Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

Reduced expression of APC and DCC gene protein in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

Aberrations of the APC gene in primary breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

The Classification of the Primates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

TCF transcription factors: molecular switches in carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

The APCI1307K allele and cancer risk in a community-based study of Ashkenazi Jews

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205892

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205892

1 reference

31 May 2018

1 reference

31 May 2018