(Q54538841)

English

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes.

scientific article published in April 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

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Catherine Arden

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Catherine Arden

1

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ORCID Public Data File 2021

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Susan J Tudhope

2

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

John L Petrie

3

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Ziad H Al-Oanzi

4

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Kirsty S Cullen

5

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Alex J Lange

6

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Howard C Towle

7

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Loranne Agius

8

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

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publication date

1 April 2012

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Biochemical Journal

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

443

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

1

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

111-123

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

Glycolysis revisited

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose as a regulator of eukaryotic gene transcription

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

An extended Myc network contributes to glucose homeostasis in cancer and diabetes.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Stimulation of glucose-6-phosphatase gene expression by glucose and fructose-2,6-bisphosphate

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Regulation of the glucose-6-phosphatase gene by glucose occurs by transcriptional and post-transcriptional mechanisms. Differential effect of glucose and xylitol

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose-6-phosphatase catalytic subunit gene family

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Selective versus total insulin resistance: a pathogenic paradox

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP).

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Upregulation of hepatic glucose 6-phosphatase gene expression in rats treated with an inhibitor of glucose-6-phosphate translocase

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

An enzymatic fluorimetric assay for glucose-6-phosphate: application in an in vitro Warburg-like effect

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Synthesis of deoxyglucose-1-phosphate, deoxyglucose-1,6-bisphosphate, and other metabolites of 2-deoxy-D-[14C]glucose in rat brain in vivo: influence of time and tissue glucose level

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Nutrient and hormonal regulation of pyruvate kinase gene expression

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Metabolism-independent sugar effects on gene transcription: the role of 3-O-methylglucose

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Transcriptional glucose signaling through the glucose response element is mediated by the pentose phosphate pathway.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Hepatic glucose sensing via the CREB coactivator CRTC2.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111280

21 January 2018

Identifiers

10.1042/BJ20111280

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22214556

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