(Q54540296)

English

Preclinical pharmacokinetics of MEHD7945A, a novel EGFR/HER3 dual-action antibody, and prediction of its human pharmacokinetics and efficacious clinical dose.

scientific article

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scholarly article

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Preclinical pharmacokinetics of MEHD7945A, a novel EGFR/HER3 dual-action antibody, and prediction of its human pharmacokinetics and efficacious clinical dose. (English)

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Amrita V Kamath

1

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Dan Lu

2

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Priyanka Gupta

3

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Denise Jin

4

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Hong Xiang

5

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Anne Wong

6

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Cecilia Leddy

7

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Lisa Crocker

8

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Gabriele Schaefer

9

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Mark X Sliwkowski

10

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Lisa A Damico-Beyer

11

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

publication date

28 December 2011

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

Cancer Chemotherapy and Pharmacology

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

69

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

4

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

1063-1069

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

https://scigraph.springernature.com/pub.10.1007/s00280-011-1806-6

0 references

ErbB receptors and signaling pathways in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

EGFR antagonists in cancer treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Targeting HER proteins in cancer therapy and the role of the non-target HER3.

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

The HER family and cancer: emerging molecular mechanisms and therapeutic targets

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Animal scale-up

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data: what have we learned?

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Interspecies scaling of protein drugs: prediction of clearance from animals to humans

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Population pharmacokinetics of therapeutic monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1806-6

21 January 2018

Identifiers

10.1007/S00280-011-1806-6

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22203367

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