(Q54563159)

English

PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.

scientific article published in February 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

left ventricular hypertrophy

1 reference

based on heuristic

inferred from title

Michael G. Irwin

8

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Paul Michel Georges Remi Vanhoutte

7

object named as

Paul M Vanhoutte

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

author name string

Yanan Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Shaoqing Lei

2

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Xia Gao

3

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Xiaowen Mao

4

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Tingting Wang

5

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Gordon T Wong

6

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Zhengyuan Xia

9

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

language of work or name

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publication date

1 February 2012

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Clinical Science

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

122

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

4

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

161-173

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

Diabetic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Metabolic disturbances in diabetic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Hyperglycemia inhibits capacitative calcium entry and hypertrophy in neonatal cardiomyocytes

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Hyperglycemia and cardiovascular disease in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Hyperglycemia as a risk factor for cardiovascular disease in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Oxidant signals and oxidative stress

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Vascular NAD(P)H oxidases: specific features, expression, and regulation

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

NAD(P)H oxidase: role in cardiovascular biology and disease

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

NAD(P)H oxidase activity in human neutrophils stimulated by phorbol myristate acetate

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Differential expression of protein kinase C isoforms in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

A novel potential therapy for diabetic nephropathy and vascular complications: protein kinase C beta inhibition

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

FGF2 signaling is required for the development of neuronal circuits regulating blood pressure.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

PKC-B inhibition: a new therapeutic approach for diabetic complications?

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Prevention of angiotensin II-induced hypertension, cardiovascular hypertrophy and oxidative stress by acetylsalicylic acid in rats

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Left ventricular hypertrophy: pathogenesis, detection, and prognosis

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Atrial myocardial nox2 containing NADPH oxidase activity contribution to oxidative stress in mitral regurgitation: potential mechanism for atrial remodeling.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

NADPH oxidases in cardiovascular health and disease

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Vascular NADPH oxidases: molecular mechanisms of activation.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Upregulation of PKC genes and isozymes in cardiovascular tissues during early stages of experimental diabetes

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic Nephropathy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Protein kinase C-beta contributes to NADPH oxidase activation in neutrophils

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Plasma 15-F2t isoprostane concentrations are increased during acute fructose loading in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Cardioprotective effect of vitamin E: rescues of diabetes-induced cardiac malfunction, oxidative stress, and apoptosis in rat.

1 reference

https://api.crossref.org/works/10.1042%2FCS20110176

21 January 2018

Identifiers

10.1042/CS20110176

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21892921

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