(Q54566056)

1 June 2018

title

Mutagenesis and chemical rescue indicate residues involved in beta-aspartyl-AMP formation by Escherichia coli asparagine synthetase B. (English)

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1 June 2018

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Boehlein SK

1

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1 June 2018

Walworth ES

series ordinal

2

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1 June 2018

Richards NG

series ordinal

3

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1 June 2018

Schuster SM

series ordinal

4

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1 June 2018

language of work or name

English

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publication date

1 May 1997

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1 June 2018

Journal of Biological Chemistry

published in

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1 June 2018

volume

272

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1 June 2018

issue

19

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1 June 2018

page(s)

12384-12392

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1 June 2018

Studies of the ammonia-dependent reaction of beef pancreatic asparagine synthetase.

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Probing the mechanism of nitrogen transfer in Escherichia coli asparagine synthetase by using heavy atom isotope effects.

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Glutamic acid gamma-monohydroxamate and hydroxylamine are alternate substrates for Escherichia coli asparagine synthetase B.

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Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs.

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Direct Brønsted analysis of the restoration of activity to a mutant enzyme by exogenous amines

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Guanidine derivatives restore activity to carboxypeptidase lacking arginine‐127

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Major contribution of a carboxymethyl group to transition-state stabilization by cytidine deaminase: mutation and rescue.

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Rescue of the catalytic activity of an H42A mutant of horseradish peroxidase by exogenous imidazoles

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Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant

21 January 2018

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Chemical rescue of Asp237-->Ala and Lys358-->Ala mutants in the lactose permease of Escherichia coli

21 January 2018

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Exogenous acetate reconstitutes the enzymatic activity of trypsin Asp189Ser

21 January 2018

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Site-directed mutagenesis of yeast phosphoglycerate kinase. The 'basic-patch' residue arginine 168.

21 January 2018

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Mutational and proteolytic studies on a flexible loop in glutathione synthetase from Escherichia coli B: the loop and arginine 233 are critical for the catalytic reaction.

21 January 2018

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Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 Å resolution

21 January 2018

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Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate

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Structural basis of the allosteric behaviour of phosphofructokinase

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Active site residues of human brain hexokinase as studied by site-specific mutagenesis

21 January 2018

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Mechanism of adenylate kinase. Structural and functional roles of the conserved arginine-97 and arginine-132.

21 January 2018

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Activation of methionine by Escherichia coli methionyl-tRNA synthetase.

21 January 2018

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Crystal structure of the active site of ribulose-bisphosphate carboxylase

21 January 2018

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Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and

21 January 2018

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Chemical rescue by exogenous amines of a site-directed mutant of ribulose 1,5-bisphosphate carboxylase/oxygenase that lacks a key lysyl residue

21 January 2018

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Identification of arginine residues in the putative L-aspartate binding site of Escherichia coli adenylosuccinate synthetase

21 January 2018

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Crystal structure of Escherichia coli thymidylate synthase containing bound 5-fluoro-2'-deoxyuridylate and 10-propargyl-5,8-dideazafolate

21 January 2018

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The class II aminoacyl-tRNA synthetases and their active site: evolutionary conservation of an ATP binding site

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.19.12384

1 reference

1 June 2018

1 reference

1 June 2018