(Q54572791)

1 June 2018

title

Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP. (English)

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5

Massimo Loda

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1 June 2018

6

Charles S Fuchs

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1 June 2018

Gregory J Kirkner

3

object named as

Gregory J Kirkner

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1 June 2018

Shuji Ogino

1

object named as

Shuji Ogino

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1 June 2018

author name string

Takako Kawasaki

2

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1 June 2018

Taiki Yamaji

4

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1 June 2018

publication date

3 November 2006

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1 June 2018

published in

Modern Pathology

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1 June 2018

volume

20

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1 June 2018

issue

1

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1 June 2018

page(s)

15-22

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1 June 2018

Modulation of cell cycle components by epigenetic and genetic events

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases

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Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis

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Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands

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CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.

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BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum

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Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

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CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

21 January 2018

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Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.

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Association of JC virus T-antigen expression with the methylator phenotype in sporadic colorectal cancers

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Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.

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Colorectal carcinomas with high microsatellite instability: defining a distinct immunologic and molecular entity with respect to prognostic markers.

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Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations

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Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer

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Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

21 January 2018

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CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations

21 January 2018

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Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer

21 January 2018

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21 January 2018

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An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

21 January 2018

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21 January 2018

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Prognostic significance of p27(kip-1) expression in colorectal adenocarcinomas is associated with tumor stage

21 January 2018

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CpG island methylator phenotype in cancer

21 January 2018

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7 January 2021

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

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7 January 2021

Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

Analysis of methylated genes in peritoneal fluids of ovarian cancer patients: a new prognostic tool

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochemistry

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800709

7 January 2021

10.1038/MODPATHOL.3800709

Identifiers

DOI

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1 June 2018

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1 June 2018