(Q54584717)

English

Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2.

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21645153%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21645153%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

0 references

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

author name string

C Pepper

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

J G Mahdi

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

A G S Buggins

3

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

S Hewamana

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

E Walsby

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

E Mahdi

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

A Al-Haza'a

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

A J Mahdi

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

T T Lin

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

L Pearce

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

I D Bowen

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

C Fegan

14

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

publication date

6 June 2011

1 reference

Europe PubMed Central

PubMed publication ID

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3 February 2020

Cell Proliferation

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

44

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

380-390

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

Update on the biology of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Re-establishment of a normal apoptotic process as a therapeutic approach in B-CLL.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Bcl-2 family gene modulation during spontaneous apoptosis of B-chronic lymphocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

The role of Bcl-2 family proteins in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Purine analogue-based chemotherapy regimens for patients with previously untreated B-chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Therapy-related acute myeloid leukemia after single-agent treatment with fludarabine for chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Purine analogue-based chemotherapy regimens for second-line therapy in patients with chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Emerging drugs for chronic lymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Caffeic acid phenethyl ester (CAPE) analogues: potent nitric oxide inhibitors from the Netherlands propolis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Nitric oxide is synthesized in acute leukemia cells after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Calcium salicylate-mediated apoptosis in human HT-1080 fibrosarcoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Antioxidant and antiproliferative activities of strawberries.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Opposing effects of aspirin and acetaminophen use on risk of adult acute leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Cyclooxygenase-2 promotes angiogenesis by increasing vascular endothelial growth factor and predicts prognosis in gallbladder carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Expression of Cyclooxygenase-2 and Bcl-2 in human gastric adenomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Potential pathogenetic implications of cyclooxygenase-2 overexpression in B chronic lymphoid leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

R-etodolac (SDX-101) and the related indole-pyran analogues SDX-308 and SDX-309 potentiate the antileukemic activity of standard cytotoxic agents in primary chronic lymphocytic leukaemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

SDX-308 and SDX-101, non-steroidal anti-inflammatory drugs, as therapeutic candidates for treating hematologic malignancies including myeloma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Sub-millimolar concentration of the novel phenol-based compound, 2-hydroxy benzoate zinc, induces apoptosis in human HT-1080 fibrosarcoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation andDe novoGene Transcription

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Structure of the human cyclo-oxygenase-2 gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Aspirin induces apoptosis in human leukemia cells independently of NF-kappaB and MAPKs through alteration of the Mcl-1/Noxa balance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

The cellular biology of B-cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2011.00760.X

21 January 2018

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological inhibitors of NF-κB accelerate apoptosis in chronic lymphocytic leukaemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-steroidal anti-inflammatory drug use and risk of adult leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenolic compounds, sodium salicylate and related compounds, as inhibitors of tumor cell growth and inducers of apoptosis in mouse leukemia L1210 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic Lymphocytic Leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of clinical chemoresistance by bcl-2 and bax oncoproteins in B-cell chronic lymphocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2184.2011.00760.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495986&resulttype=core&format=json

14 May 2020

ResearchGate publication ID

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