(Q54589616)

1 June 2018

title

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury. (English)

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Praveen Anand

1

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Ravikiran Shenoy

2

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Joanne E Palmer

3

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Amanda J Baines

4

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Robert Y K Lai

5

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Jonathan Robertson

6

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Nick Bird

7

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Thor Ostenfeld

8

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Boris A Chizh

9

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publication date

14 May 2011

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1 June 2018

published in

European Journal of Pain

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volume

15

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issue

10

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page(s)

1040-1048

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Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.

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Current options for nonsurgical management of carpal tunnel syndrome

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Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis

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Incidence rates and treatment of neuropathic pain conditions in the general population

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Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study

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Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy

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Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens

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Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

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p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

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Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies

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Local corticosteroid injection for carpal tunnel syndrome

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TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

21 January 2018

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Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

21 January 2018

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Single-dose pharmacokinetics and pharmacodynamics of RWJ 67657, a specific p38 mitogen-activated protein kinase inhibitor: a first-in-human study.

21 January 2018

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Microglial signalling cascades in neurodegenerative disease.

21 January 2018

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Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

21 January 2018

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Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model

21 January 2018

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Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia

21 January 2018

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Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

21 January 2018

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Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

21 January 2018

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10.1016/J.EJPAIN.2011.04.005

21 January 2018

Identifiers

DOI

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1 June 2018

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1 June 2018