(Q54594062)

1 June 2018

title

KIT gene mutation and amplification in dysgerminoma of the ovary. (English)

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1 June 2018

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8

Rodolfo Montironi

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1 June 2018

1

Liang Cheng

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1 June 2018

Antonio Lopez-Beltran

9

object named as

Antonio Lopez-Beltran

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1 June 2018

author name string

Lawrence M Roth

2

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1 June 2018

Shaobo Zhang

3

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1 June 2018

Mingsheng Wang

4

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1 June 2018

Michael J Morton

5

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1 June 2018

Wenxin Zheng

6

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1 June 2018

Fadi W Abdul Karim

7

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1 June 2018

language of work or name

English

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publication date

30 November 2010

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1 June 2018

published in

Cancer

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1 June 2018

volume

117

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1 June 2018

issue

10

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1 June 2018

page(s)

2096-2103

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1 June 2018

Activating c-kit gene mutations in human germ cell tumors

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Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

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STAT protein recruitment and activation in c-Kit deletion mutants

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Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature

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KIT mutations are common in testicular seminomas

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Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers

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c-KIT codon 816 mutation in a recurrent and metastatic dysgerminoma of a 14-year-old girl: case study

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c-kit gene mutations in intracranial germinomas

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Alterations of the c-kit gene in testicular germ cell tumors

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Detection of c-kit exons 11- and 17-activating mutations in testicular seminomas by high-resolution melting amplicon analysis.

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Recent advances in the pathology and classification of ovarian germ cell tumors

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Germ cell tumors of the ovary

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Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors

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Amplifications of EGFR gene and protein expression of EGFR, Her-2/neu, c-kit, and androgen receptor in phyllodes tumor of the prostate

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Fluorescence in situ hybridization analysis of chromosome 12p in paraffin-embedded tissue is useful for establishing germ cell origin of metastatic tumors.

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Molecular genetic evidence supporting the neoplastic nature of stromal cells in 'fibrosis' after chemotherapy for testicular germ cell tumours

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Expression of CD117 (c-kit) receptor in dysgerminoma of the ovary: diagnostic and therapeutic implications

21 January 2018

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Prevalence of KIT expression in human tumors

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Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults

21 January 2018

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Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type

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KIT mutations induce intracellular retention and activation of an immature form of the KIT protein in gastrointestinal stromal tumors

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Prognostic significance of c-kit mutation in localized gastrointestinal stromal tumors

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Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis.

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Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site

21 January 2018

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Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS).

21 January 2018

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Analysis of protein expression and gene mutation of c-kit in colorectal neuroendocrine carcinomas

21 January 2018

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Gonadoblastoma: evidence for a stepwise progression to dysgerminoma in a dysgenetic ovary

21 January 2018

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Chromosome 12p abnormalities in dysgerminoma of the ovary: a FISH analysis

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.25794

c-KIT is frequently mutated in bilateral germ cell tumours and down-regulated during progression from intratubular germ cell neoplasia to seminoma

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.25794

OCT4: a novel biomarker for dysgerminoma of the ovary

21 January 2018

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7 January 2021

Somatic mutations of KIT in familial testicular germ cell tumours

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https://api.crossref.org/works/10.1002%2FCNCR.25794

7 January 2021

KIT (c-kit oncogene product) pathway is constitutively activated in human testicular germ cell tumors

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7 January 2021

Primary mediastinal seminomas: evidence of single and multiple KIT mutations

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7 January 2021

Hereditary gastrointestinal stromal tumors sharing the KIT Exon 17 germline mutation p.Asp820Tyr develop through different cytogenetic progression pathways

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https://api.crossref.org/works/10.1002%2FCNCR.25794

7 January 2021

Interphase fluorescence in situ hybridization analysis of chromosome 12p abnormalities is useful for distinguishing epidermoid cysts of the testis from pure mature teratoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.25794

7 January 2021

Expression of the c-kit proto-oncogene and its ligand stem cell factor (SCF) in normal and malignant human testicular tissue

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.25794

7 January 2021

Expression and mutation of c-kit gene in gastrointestinal stromal tumors

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https://api.crossref.org/works/10.1002%2FCNCR.25794

7 January 2021

Identifiers

DOI

10.1002/CNCR.25794

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1 June 2018

PubMed ID

21523721

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1 June 2018