(Q54610580)

1 June 2018

title

Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway. (English)

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1 June 2018

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2

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author name string

C Zhang

1

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S Lokireddy

3

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S Bonala

4

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X Ge

5

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S Masuda

6

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P D Gluckman

7

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M Sharma

8

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R Kambadur

9

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publication date

24 February 2011

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1 June 2018

published in

Diabetologia

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volume

54

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issue

6

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1 June 2018

page(s)

1491-1501

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1 June 2018

https://scigraph.springernature.com/pub.10.1007/s00125-011-2079-7

exact match

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cites work

Prolonged absence of myostatin reduces sarcopenia

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12 December 2020

Loss of myostatin expression alters fiber-type distribution and expression of myosin heavy chain isoforms in slow- and fast-type skeletal muscle

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12 December 2020

Myostatin negatively regulates satellite cell activation and self-renewal

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12 December 2020

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

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12 December 2020

Increased secretion and expression of myostatin in skeletal muscle from extremely obese women.

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12 December 2020

Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice

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12 December 2020

Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin

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12 December 2020

Myostatin decreases with aerobic exercise and associates with insulin resistance

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12 December 2020

Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells

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12 December 2020

AMP-activated protein kinase and the regulation of glucose transport

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12 December 2020

Myostatin Knockout in Mice Increases Myogenesis and Decreases Adipogenesis

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12 December 2020

Malonyl-CoA, fuel sensing, and insulin resistance

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12 December 2020

Regulation of muscle growth by multiple ligands signaling through activin type II receptors

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12 December 2020

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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12 December 2020

Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice

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12 December 2020

Myostatin mutation associated with gross muscle hypertrophy in a child

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12 December 2020

Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance

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12 December 2020

AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle

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12 December 2020

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

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12 December 2020

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice

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12 December 2020

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

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12 December 2020

Double muscling in cattle due to mutations in the myostatin gene

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12 December 2020

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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12 December 2020

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

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12 December 2020

Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity

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12 December 2020

Induction of cachexia in mice by systemically administered myostatin.

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12 December 2020

A soluble activin type IIB receptor improves function in a mouse model of amyotrophic lateral sclerosis

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12 December 2020

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

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12 December 2020

Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles

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12 December 2020

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

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12 December 2020

AMP-activated protein kinase--the fat controller of the energy railroad

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12 December 2020

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

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12 December 2020

Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct

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12 December 2020

Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance

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12 December 2020

Myostatin inhibits myoblast differentiation by down-regulating MyoD expression.

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12 December 2020

Regulation of myostatin activity and muscle growth

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12 December 2020

5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.

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Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle.

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12 December 2020

Suppression of body fat accumulation in myostatin-deficient mice

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12 December 2020

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

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12 December 2020

Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation

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12 December 2020

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism.

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12 December 2020

10.1007/S00125-011-2079-7

Identifiers

DOI

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1 June 2018

PubMed ID

21347623

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1 June 2018