(Q36602598)

15 August 2017

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title

AMP-activated protein kinase--the fat controller of the energy railroad (English)

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15 August 2017

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Bruce E Kemp

4

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author name string

Gregory R Steinberg

series ordinal

1

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PubMed ID

16998529

15 August 2017

S Lance Macaulay

series ordinal

2

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PubMed ID

16998529

15 August 2017

Mark A Febbraio

series ordinal

3

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15 August 2017

1 July 2006

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Canadian Journal of Physiology and Pharmacology

15 August 2017

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15 August 2017

84

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15 August 2017

7

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15 August 2017

655-665

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Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms

15 August 2017

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Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms

21 January 2018

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The subcellular localization of acetyl-CoA carboxylase 2

21 January 2018

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Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

21 January 2018

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Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

21 January 2018

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Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

21 January 2018

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Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site

21 January 2018

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Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle

21 January 2018

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AMP-activated protein kinase plays a role in the control of food intake

21 January 2018

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Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

21 January 2018

1 reference

Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro

21 January 2018

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Regulation of fasted blood glucose by resistin

21 January 2018

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Regulation of fatty acid transport and membrane transporters in health and disease

21 January 2018

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Regulation of fatty acid transport by fatty acid translocase/CD36

21 January 2018

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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

21 January 2018

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A yeast gene that is essential for release from glucose repression encodes a protein kinase

21 January 2018

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The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR

21 January 2018

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Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics

21 January 2018

1 reference

Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes

21 January 2018

1 reference

Enzymes of triacylglycerol synthesis and their regulation

21 January 2018

1 reference

Impact of adenoviral transduction with SREBP1c or AMPK on pancreatic islet gene expression profile: analysis with oligonucleotide microarrays

21 January 2018

1 reference

Contractions activate hormone-sensitive lipase in rat muscle by protein kinase C and mitogen-activated protein kinase

21 January 2018

1 reference

Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation

21 January 2018

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Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.

21 January 2018

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Metformin and reduced risk of cancer in diabetic patients

21 January 2018

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A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

21 January 2018

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Activation of rat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate.

21 January 2018

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Mitochondrial glycerol phosphate acyltransferase contains two transmembrane domains with the active site in the N-terminal domain facing the cytosol.

21 January 2018

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Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway

21 January 2018

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Herbicides inhibiting acetyl-CoA carboxylase

21 January 2018

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Cloning of human acetyl-CoA carboxylase-beta and its unique features

21 January 2018

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Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line

21 January 2018

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Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition

21 January 2018

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Roles of the Snf1/Rkin1/AMP-activated protein kinase family in the response to environmental and nutritional stress.

21 January 2018

1 reference

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

21 January 2018

1 reference

Hypothalamic malonyl-CoA as a mediator of feeding behavior

21 January 2018

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Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects

21 January 2018

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AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270)

21 January 2018

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Immunological analysis of acetyl-CoA carboxylase mass, tissue distribution and subunit composition

21 January 2018

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise

21 January 2018

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Evidence that acetyl-CoA carboxylase isoforms play different biological roles in H9c2 cardiomyocyte

21 January 2018

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Regulation of mammalian acetyl-coenzyme A carboxylase

21 January 2018

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5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle

21 January 2018

1 reference

Expression of hormone-sensitive lipase and its regulation by adrenaline in skeletal muscle

21 January 2018

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Stimulation of hormone-sensitive lipase activity by contractions in rat skeletal muscle

21 January 2018

1 reference

How obesity causes diabetes: not a tall tale

21 January 2018

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Biosynthesis of triacylglycerols

21 January 2018

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Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria

21 January 2018

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Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle

21 January 2018

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Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis

21 January 2018

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Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors

21 January 2018

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Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

21 January 2018

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Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters

21 January 2018

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The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

21 January 2018

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

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The fatty acid translocase (FAT)/CD36 and the glucose transporter GLUT4 are localized in different cellular compartments in rat cardiac muscle

21 January 2018

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Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

21 January 2018

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AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.

21 January 2018

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Role of resistin in diet-induced hepatic insulin resistance

21 January 2018

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Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A. Formation of Equimolar Enzyme-Inhibitor Complex

21 January 2018

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Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liver.

21 January 2018

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Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice

21 January 2018

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Regulation of fatty acid uptake and metabolism in L6 skeletal muscle cells by resistin

21 January 2018

1 reference

Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise

21 January 2018

1 reference

Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro

21 January 2018

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Structural basis for glycogen recognition by AMP-activated protein kinase

21 January 2018

1 reference

Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise.

21 January 2018

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AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome

21 January 2018

1 reference

Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.

21 January 2018

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Effects of streptozotocin-diabetes and insulin administration in vivo or in vitro on the activities of five enzymes in the adipose-tissue triacylglycerol-synthesis pathway

21 January 2018

1 reference

Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5'AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique

21 January 2018

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Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene.

21 January 2018

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AMP kinase-induced skeletal muscle glucose but not long-chain fatty acid uptake is dependent on nitric oxide

21 January 2018

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Heart-type fatty acid-binding protein reciprocally regulates glucose and fatty acid utilization during exercise

21 January 2018

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Cellular mechanisms of insulin resistance

21 January 2018

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AMP kinase activation with AICAR further increases fatty acid oxidation and blunts triacylglycerol hydrolysis in contracting rat soleus muscle.

21 January 2018

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Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system

21 January 2018

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Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats

21 January 2018

1 reference

AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females

21 January 2018

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The fatty acid transport function of fatty acid-binding proteins

21 January 2018

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Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

21 January 2018

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C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity

21 January 2018

1 reference

Purification and characterization of rat skeletal muscle acetyl-CoA carboxylase

21 January 2018

1 reference

Effects of Plasma Adrenaline on Hormone‐Sensitive Lipase at Rest and during Moderate Exercise in Human Skeletal Muscle

21 January 2018

1 reference

Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle

21 January 2018

1 reference

Identification of a second human acetyl-CoA carboxylase gene

21 January 2018

1 reference

Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes

21 January 2018

1 reference

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis In 3T3-L1 adipocytes

21 January 2018

1 reference

Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/Y06-005

1 reference

15 August 2017

1 reference

PubMed ID

16998529