(Q54631038)

1 June 2018

title

A soluble pyrophosphatase, a key enzyme for polyphosphate metabolism in Leishmania. (English)

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1 June 2018

author name string

Benoît Espiau

1

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1 June 2018

Guillaume Lemercier

2

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Audrey Ambit

3

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Frédéric Bringaud

4

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1 June 2018

Gilles Merlin

5

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1 June 2018

Théo Baltz

6

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1 June 2018

Norbert Bakalara

7

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language of work or name

English

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publication date

15 November 2005

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1 June 2018

Journal of Biological Chemistry

published in

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volume

281

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issue

3

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page(s)

1516-1523

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1 June 2018

A pyrophosphatase regulating polyphosphate metabolism in acidocalcisomes is essential for Trypanosoma brucei virulence in mice

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Formation of an actin-like filament concurrent with the enzymatic synthesis of inorganic polyphosphate

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A vacuolar-type H+-pyrophosphatase governs maintenance of functional acidocalcisomes and growth of the insect and mammalian forms of Trypanosoma brucei

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An acidocalcisomal exopolyphosphatase from Leishmania major with high affinity for short chain polyphosphate

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Rapid changes in polyphosphate content within acidocalcisomes in response to cell growth, differentiation, and environmental stress in Trypanosoma cruzi

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The structural basis for pyrophosphatase catalysis

21 January 2018

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Identification of an infective stage of Leishmania promastigotes.

21 January 2018

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Sphingolipids are essential for differentiation but not growth in Leishmania

21 January 2018

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21 January 2018

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The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications

21 January 2018

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A novel calcium-dependent soluble inorganic pyrophosphatase from the trypanosomatid Leishmania major.

21 January 2018

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Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M506947200

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1 June 2018

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1 June 2018