(Q54631097)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Robyn Ward

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Justin J L Wong

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Megan P Hitchins

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

publication date

19 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

396-411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21102416%20AND%20SRC:MED&resulttype=core&format=json

Colorectal cancer: a model for epigenetic tumorigenesis

16 January 2020

cites work

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21 January 2018

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BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer

21 January 2018

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21 January 2018

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

21 January 2018

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Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

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Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

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Deletion mapping using quantitative real-time PCR identifies two distinct 3p21.3 regions affected in most cervical carcinomas

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Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas

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Silencing of bidirectional promoters by DNA methylation in tumorigenesis

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DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

21 January 2018

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The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.

21 January 2018

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CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Germline epimutation of MLH1 in individuals with multiple cancers

21 January 2018

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MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer

21 January 2018

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Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

21 January 2018

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BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer

21 January 2018

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21 January 2018

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Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

21 January 2018

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MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer

21 January 2018

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MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

21 January 2018

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Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021