(Q54644240)

English

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

type 2 diabetes

0 references

0 references

phosphorylation

0 references

1 reference

based on heuristic

inferred from title

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Jonas T. Treebak

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Jørgen Wojtaszewski

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

B F Vind

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

C Pehmøller

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

M Hey-Mogensen

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

H Beck-Nielsen

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

K Højlund

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

13 October 2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

54

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

157-167

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20938636%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-010-1924-4

0 references

Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators of insulin resistance in type 2 diabetes?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1924-4

21 January 2018

Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1924-4

21 January 2018

Critical nodes in signalling pathways: insights into insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between muscle fibre composition, glucose transporter protein 4 and exercise training: possible consequences in non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of 5'AMP-activated protein kinase in skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise-Induced Phosphorylation of the Novel Akt Substrates AS160 and Filamin A in Human Skeletal Muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AS160 phosphorylation is associated with activation of alpha2beta2gamma1- but not alpha2beta2gamma3-AMPK trimeric complex in skeletal muscle during exercise in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Four grams of glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptations to exercise training within skeletal muscle in adults with type 2 diabetes or impaired glucose tolerance: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximal lipid oxidation in patients with type 2 diabetes is normal and shows an adequate increase in response to aerobic training.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated muscle glucose clearance in patients with NIDDM. Effects of one-legged physical training

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin Signaling and Glucose Transport in Skeletal Muscle From First-Degree Relatives of Type 2 Diabetic Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20938636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q54644240&oldid=1838915164"