(Q54650268)

2 June 2018

title

A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes. (English)

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2 June 2018

Karim J Brandt

1

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author name string

Rakel Carpintero

2

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2 June 2018

Lyssia Gruaz

3

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2 June 2018

Nicolas Molnarfi

4

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2 June 2018

Danielle Burger

5

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2 June 2018

publication date

13 September 2010

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2 June 2018

Journal of Leukocyte Biology

published in

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2 June 2018

volume

88

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2 June 2018

issue

6

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2 June 2018

page(s)

1191-1200

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2 June 2018

Is IL-1 a good therapeutic target in the treatment of arthritis?

cites work

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

A pilot study of IL-1 inhibition by anakinra in acute gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Induction of serum soluble tumor necrosis factor receptor II (sTNF-RII) and interleukin-1 receptor antagonist (IL-1ra) by interferon beta-1b in patients with progressive multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Mechanisms of type-I- and type-II-interferon-mediated signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Akt and mRNA translation by interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Signaling by distinct classes of phosphoinositide 3-kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Differential regulation of cytokine production by PI3Kdelta in human monocytes upon acute and chronic inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

ERK implication in cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Mek2 is dispensable for mouse growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The MAP kinase pathway is required for entry into mitosis and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Mek1 alters epidermal growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

The p110delta isoform of PI3K differentially regulates beta1 and beta2 integrin-mediated monocyte adhesion and spreading and modulates diapedesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

MAP kinase: it's been longer than fifteen minutes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Structure of the PI3K SH3 domain and analysis of the SH3 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

p110δ, a novel phosphoinositide 3-kinase in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

A PI-3 kinase-dependent, Stat1-independent signaling pathway regulates interferon-stimulated monocyte adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Regulation of Akt/PKB Ser473 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Protein kinase B/Akt at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0510312

21 January 2018

Identifiers

DOI

10.1189/JLB.0510312

1 reference

2 June 2018

1 reference

2 June 2018