(Q54665731)

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Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo? (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

rheumatoid arthritis

1 reference

based on heuristic

inferred from title

author name string

Theresa H Page

1

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Anthony Brown

2

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Emma M Timms

3

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Brian M J Foxwell

4

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Keith P Ray

5

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

publication date

1 November 2010

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Arthritis and Rheumatism

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

62

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

11

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

3221-3231

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

Many cytokines are very useful therapeutic targets in disease

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The therapeutic potential of TNF-alpha blockade in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Joint inflammation and cytokine inhibition in rheumatoid arthritis

1 reference

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21 January 2018

Cytokine inhibitors in the treatment of rheumatoid arthritis

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

p38 MAP-kinases pathway regulation, function and role in human diseases

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Structural comparison of p38 inhibitor-protein complexes: a review of recent p38 inhibitors having unique binding interactions

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The selectivity of protein kinase inhibitors: a further update

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

MAPKs and their relevance to arthritis and inflammation

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

A quantitative analysis of kinase inhibitor selectivity

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activate

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Cells of the synovium in rheumatoid arthritis. Macrophages

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The p38 signal transduction pathway: activation and function

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Mechanisms of mRNA translation of interferon stimulated genes

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Inhibition of p38: has the fat lady sung?

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

A potent and selective p38 inhibitor protects against bone damage in murine collagen-induced arthritis: a comparison with neutralization of mouse TNFalpha

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

The many paths to p38 mitogen-activated protein kinase activation in the immune system

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Zcchc11-dependent uridylation of microRNA directs cytokine expression

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Immunoregulatory role of interleukin 10 in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Interleukin-6 and chronic inflammation

1 reference

https://api.crossref.org/works/10.1002%2FART.27631

21 January 2018

Identifiers

10.1002/ART.27631

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/20589681

ResearchGate publication ID

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