(Q54727272)

English

A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer. (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

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Giampaolo Tortora

1

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

Fortunato Ciardiello

8

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

author name string

R Caputo

2

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

V Damiano

3

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

R Bianco

4

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

J Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

S Agrawal

6

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

A R Bianco

7

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

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publication date

1 December 2000

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Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

International Journal of Cancer

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Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

88

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

5

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

804-809

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes

1 reference

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21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

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21 January 2018

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

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21 January 2018

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

p53-independent role of MDM2 in TGF-beta1 resistance

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A.

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Antisense therapeutics

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Abnormal expression of MDM-2 in breast carcinomas

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Large-scale synthesis, purification, and analysis of oligodeoxynucleotide phosphorothioates

1 reference

https://api.crossref.org/works/10.1002%2F1097-0215%2820001201%2988%3A5%3C804%3A%3AAID-IJC19%3E3.0.CO%3B2-Z

21 January 2018

Identifiers

10.1002/1097-0215(20001201)88:5<804::AID-IJC19>3.0.CO;2-Z

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 June 2018

http://europepmc.org/abstract/MED/11072252

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