(Q54976951)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

Diogo de Barros Peruchetti

30 March 2020

author

1

1 reference

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Rodrigo Pacheco Silva-Aguiar

30 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Wagner B Dias

4

1 reference

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30 March 2020

Celso Caruso-Neves

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

author name string

Gabriela Marques Siqueira

3

1 reference

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30 March 2020

language of work or name

English

0 references

publication date

5 June 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

293

1 reference

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30 March 2020

issue

29

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30 March 2020

page(s)

11388-11400

1 reference

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Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase

30 March 2020

cites work

1 reference

12 December 2020

Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats

1 reference

12 December 2020

High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases

1 reference

12 December 2020

Angiotensin II blockade restores albumin reabsorption in the proximal tubules of diabetic rats

1 reference

12 December 2020

Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

1 reference

12 December 2020

High glucose reduces albumin uptake in cultured proximal tubular cells (LLC-PK1).

1 reference

12 December 2020

Renal tubule albumin transport

1 reference

12 December 2020

Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

1 reference

12 December 2020

Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation

1 reference

12 December 2020

Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1).

1 reference

12 December 2020

How does proteinuria cause progressive renal damage?

1 reference

12 December 2020

PKB and megalin determine the survival or death of renal proximal tubule cells

1 reference

12 December 2020

High glucose initiates calpain-induced necrosis before apoptosis in LLC-PK1 cells

1 reference

12 December 2020

Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury

1 reference

12 December 2020

Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation

1 reference

12 December 2020

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

1 reference

12 December 2020

Evidence of O-linked N-acetylglucosamine in diabetic nephropathy.

1 reference

12 December 2020

O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation

1 reference

12 December 2020

Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.

1 reference

12 December 2020

Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling

1 reference

12 December 2020

Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes

1 reference

12 December 2020

Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells.

1 reference

12 December 2020

O-GlcNAcylation of tubulin inhibits its polymerization.

1 reference

12 December 2020

Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats

1 reference

12 December 2020

Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease

1 reference

12 December 2020

Diabetic tubulopathy: an emerging entity.

1 reference

12 December 2020

Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including α-actinin 4

1 reference

12 December 2020

Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease

1 reference

12 December 2020

(Na+ + K+)-ATPase is a target for phosphoinositide 3-kinase/protein kinase B and protein kinase C pathways triggered by albumin.

1 reference

12 December 2020

PKB/Akt partners with Dab2 in albumin endocytosis

1 reference

12 December 2020

Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications

1 reference

12 December 2020

O-GlcNAcylation of kinases

1 reference

12 December 2020

The pathogenic role of the renal proximal tubular cell in diabetic nephropathy

1 reference

12 December 2020

O-GlcNAcylation and oxidation of proteins: is signalling in the cardiovascular system becoming sweeter?

1 reference

12 December 2020

CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies.

1 reference

12 December 2020

Proteinuria: Tubular handling of albumin-degradation or salvation?

1 reference

12 December 2020

The proximal tubule and albuminuria: really!

1 reference

12 December 2020

Albuminuria is controlled primarily by proximal tubules

1 reference

12 December 2020

Reply: podocytes are key-although albumin never reaches the slit diaphragm

1 reference

12 December 2020

Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules

1 reference

12 December 2020

Retracted: Impaired Insulin Signaling Affects Renal Organic Anion Transporter 3 (Oat3) Function in Streptozotocin-Induced Diabetic Rats

1 reference

12 December 2020

O-GlcNAcylation: The Sweet Side of the Cancer

1 reference

12 December 2020

Progression of renal injury toward interstitial inflammation and glomerular sclerosis is dependent on abnormal protein filtration

1 reference

12 December 2020

5-Lypoxygenase products are involved in renal tubulointerstitial injury induced by albumin overload in proximal tubules in mice

1 reference

12 December 2020

Activation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury

1 reference

12 December 2020

Empagliflozin, an Inhibitor of Sodium-Glucose Cotransporter 2 Exerts Anti-Inflammatory and Antifibrotic Effects on Experimental Diabetic Nephropathy Partly by Suppressing AGEs-Receptor Axis

1 reference

12 December 2020

A little sugar goes a long way: the cell biology of O-GlcNAc

1 reference

12 December 2020

Renal tubular damage may contribute more to acute hyperglycemia induced kidney injury in non-diabetic conscious rats.

1 reference

12 December 2020

Akt/PKB: one kinase, many modifications.

1 reference

12 December 2020

The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1.

1 reference

12 December 2020

Renoprotective effects of combined SGLT2 and ACE inhibitor therapy in diabetic Dahl S rats

1 reference

12 December 2020

Streptozotocin-Induced Diabetic Models in Mice and Rats.

1 reference

12 December 2020

O-GlcNAcylation regulates ischemia-induced neuronal apoptosis through AKT signaling

1 reference

12 December 2020

Silencing of angiotensin II type-1 receptor inhibits high glucose-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via inactivation of mTOR/p70S6K signaling pathway

1 reference

12 December 2020

SGLT2 Inhibitors: Glucotoxicity and Tumorigenesis Downstream the Renal Proximal Tubule?

1 reference

12 December 2020

Transforming growth factor-β1 and diabetic nephropathy

1 reference

12 December 2020

Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease.

1 reference

12 December 2020

New insights: A role for O-GlcNAcylation in diabetic complications

1 reference

12 December 2020

High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity?

1 reference

12 December 2020

Role of O-linked N-acetylglucosamine modification in diabetic nephropathy.

1 reference

12 December 2020

Uroguanylin modulates (Na++K+)ATPase in a proximal tubule cell line: Interactions among the cGMP/protein kinase G, cAMP/protein kinase A, and mTOR pathways.

1 reference

12 December 2020

Roles of O-GlcNAc in chronic diseases of aging.

1 reference

12 December 2020

mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells

1 reference

12 December 2020

O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling

1 reference

12 December 2020

Roles of mTOR complexes in the kidney: implications for renal disease and transplantation.

1 reference

12 December 2020

Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells

1 reference

12 December 2020

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition.

1 reference

12 December 2020

Diagnosis and Management of Type 2 Diabetic Kidney Disease

1 reference

12 December 2020

Proximal Tubulopathy: Prime Mover and Key Therapeutic Target in Diabetic Kidney Disease

1 reference

12 December 2020

AKT/PKB Signaling: Navigating the Network

1 reference

12 December 2020

SGLT2 Inhibitors as a Therapeutic Option for Diabetic Nephropathy.

1 reference

12 December 2020

Modulation of heme oxygenase-1 expression and activity affects streptozotocin-induced diabetic nephropathy in rats.

1 reference

12 December 2020

Potential Role of Serum and Urinary Biomarkers in Diagnosis and Prognosis of Diabetic Nephropathy

1 reference

12 December 2020

TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin

1 reference

12 December 2020

Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration

1 reference

12 December 2020

The protective effect of shikonin on renal tubular epithelial cell injury induced by high glucose.

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.RA117.001337

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29871929%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference