(Q55024311)

15 June 2018

title

Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma. (English)

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15 June 2018

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A Suzuki

1

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15 June 2018

M Toi

2

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15 June 2018

Y Yamamoto

3

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15 June 2018

S Saji

4

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15 June 2018

M Muta

5

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15 June 2018

T Tominaga

6

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15 June 2018

publication date

1 February 1998

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15 June 2018

number of pages

7

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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15 June 2018

volume

89

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15 June 2018

issue

2

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15 June 2018

page(s)

221-227

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15 June 2018

MDM2 overexpression in benign and malignant lesions of the human breast

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

mdm2 expression is induced by wild type p53 activity

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Modulation of cell proliferation and gene expression by a p53-estrogen receptor hybrid protein

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

The p53-binding protein MDM2 gene is differentially expressed in human breast carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

The p53-mdm-2 autoregulatory feedback loop

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

WAF1, a potential mediator of p53 tumor suppression

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Identification of a p53-dependent negative response element in the bcl-2 gene

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Interaction between the retinoblastoma protein and the oncoprotein MDM2

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Mapping of the p53 and mdm-2 interaction domains

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

p53 modulation of TFIIH-associated nucleotide excision repair activity

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Amplification of a gene encoding a p53-associated protein in human sarcomas

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Immunocytochemical analysis of MDM2 protein expression and its relevance to tumor angiogenesis in primary breast cancer.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

Oncogene amplification in urothelial cancers with p53 gene mutation or MDM2 amplification.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921757

p53 status and the efficacy of cancer therapy in vivo

13 August 2018

1 reference

12 December 2020

Altered patterns of MDM2 and TP53 expression in human bladder cancer

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12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

1 reference

12 December 2020

mdm2 gene alterations and mdm2 protein expression in breast carcinomas

1 reference

12 December 2020

Dominance of wild-type p53-mediated transcriptional activation in breast epithelial cells

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12 December 2020

Differential expression of multiple MDM2 messenger RNAs and proteins in normal and tumorigenic breast epithelial cells

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12 December 2020

The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger

1 reference

12 December 2020

Infrequency of MDM2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas

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12 December 2020

MDM2 gene amplification in human breast cancer

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12 December 2020

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

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12 December 2020

10.1111/J.1349-7006.1998.TB00552.X

Identifiers

DOI

1 reference

15 June 2018

PMC publication ID

5921757

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15 June 2018

PubMed publication ID

9548451

1 reference

15 June 2018