(Q55043012)

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The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis.

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Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

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The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis. (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

obsessive-compulsive disorder

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author name string

Pooley EC

1

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

Fineberg N

2

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

Harrison PJ

3

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

language of work or name

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publication date

30 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

Molecular Psychiatry

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Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

12

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

6

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

556-561

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.

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Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

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The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons

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Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond

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Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior

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Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

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The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes

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The principal features and mechanisms of dopamine modulation in the prefrontal cortex

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Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

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A family study of obsessive-compulsive disorder.

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Obsessive-compulsive disorder

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Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder

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Gender-related clinical differences in obsessive-compulsive disorder

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Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder

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Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder

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Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder

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COMT Val158Met polymorphism in schizophrenia with obsessive-compulsive disorder: a case-control study

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Association between the dopamine D2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males

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Association between the COMT locus and obsessive-compulsive disorder in females but not males

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Whole genome amplification from a single cell: implications for genetic analysis

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No association between anxiety disorders and catechol-O-methyltransferase polymorphism

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Association between a catechol-o-methyltransferase polymorphism and obsessive-compulsive disorder in the Afrikaner population

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Lack of association of catechol-O-methyltransferase gene polymorphism in obsessive-compulsive disorder

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Association analysis of the catechol-o-methyltransferase (COMT), serotonin transporter (5-HTT) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive-compulsive disorder

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Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis

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Meta-analysis of association between a catechol-O-methyltransferase gene polymorphism and attention deficit hyperactivity disorder

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Problems of reporting genetic associations with complex outcomes

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Assessing the function of genetic variants in candidate gene association studies

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The complex interplay among factors that influence allelic association.

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Meta-analysis of the association between the catecholamine-O-methyl-transferase gene and obsessive-compulsive disorder

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Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.

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Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing

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Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation

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Catechol-O-methyltransferase genotype and dopamine regulation in the human brain.

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Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype

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The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers

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Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex.

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Human catechol-O-methyltransferase down-regulation by estradiol

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A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain

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Impact of complex genetic variation in COMT on human brain function

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Identifiers

10.1038/SJ.MP.4001951

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 June 2018

http://europepmc.org/abstract/MED/17264842

ResearchGate publication ID

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