(Q55077829)

17 June 2018

title

Contribution of exosite occupancy by heparin to the regulation of coagulation proteases by antithrombin. (English)

1 reference

17 June 2018

1 reference

L Yang

1

1 reference

17 June 2018

C Manithody

series ordinal

2

1 reference

17 June 2018

S H Qureshi

series ordinal

3

1 reference

17 June 2018

A R Rezaie

series ordinal

4

1 reference

17 June 2018

publication date

18 December 2009

1 reference

17 June 2018

Thrombosis and Haemostasis

published in

1 reference

17 June 2018

volume

103

1 reference

17 June 2018

issue

2

1 reference

17 June 2018

page(s)

277-283

1 reference

17 June 2018

Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Serpin structure, mechanism, and function

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by promoting the assembly of an intermediate heparin-antithrombin-factor Xa bridging complex. Demonstration by rapid kinetics studies

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

The anticoagulant activation of antithrombin by heparin

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Binding of factor VIIa to tissue factor permits rapid antithrombin III/heparin inhibition of factor VIIa

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Role of ternary complexes, in which heparin binds both antithrombin and proteinase, in the acceleration of the reactions between antithrombin and thrombin or factor Xa.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Exosite occupation by heparin enhances the reactivity of blood coagulation factor IXa.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Probing the molecular basis of factor Xa specificity by mutagenesis of the serpin, antithrombin

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Structural mobility of antithrombin and its modulation by heparin

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818343

Characterization of a heparin binding site on the heavy chain of factor XI

30 November 2018

1 reference

12 December 2020

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

1 reference

12 December 2020

Initial treatment of venous thromboembolism

1 reference

12 December 2020

Emerging anticoagulants for the treatment of venous thromboembolism

1 reference

12 December 2020

The heparin-binding exosite is critical to allosteric activation of factor IXa in the intrinsic tenase complex: the role of arginine 165 and factor X

1 reference

12 December 2020

Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

1 reference

12 December 2020

Localization of the heparin binding exosite of factor IXa

1 reference

12 December 2020

Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity

1 reference

12 December 2020

Anticoagulant Action of Heparin

1 reference

12 December 2020

Anticoagulantly active heparin-like molecules from vascular tissue

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH09-08-0585

1 reference

17 June 2018

PMC publication ID

2818343

1 reference

17 June 2018

PubMed publication ID

20024502

1 reference

17 June 2018