(Q5513619)

http://www.ebi.ac.uk/interpro/protein/P08151

Zinc finger C2H2 superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08151

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

sequence-specific DNA binding

1 reference

24 April 2018

A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08151&geneProductId=UniProtKB:P08151

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

9 May 2019

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

14 references

9 May 2019

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Gli regulation by the opposing activities of fused and suppressor of fused

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

The crosstalk of mTOR/S6K1 and Hedgehog pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08151&geneProductId=UniProtKB:P08151

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

9 May 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Inhibition of GLI1 gene activation by Patched1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

3 references

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Gli regulation by the opposing activities of fused and suppressor of fused

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

epidermal cell differentiation

biological process

1 reference

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

proximal/distal pattern formation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

regulation of transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08151&geneProductId=UniProtKB:P08151

positive regulation of smoothened signaling pathway

1 reference

9 May 2019

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of cell migration

1 reference

24 April 2018

A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08151&geneProductId=UniProtKB:P08151

smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08151&geneProductId=UniProtKB:P08151

positive regulation of transcription, DNA-templated

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of DNA replication

1 reference

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

ventral midline development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

regulation of smoothened signaling pathway

1 reference

9 May 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

regulation of osteoblast differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

osteoblast differentiation

1 reference

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

cerebellar cortex morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

regulation of hepatocyte proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

canonical Wnt signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

smoothened signaling pathway

4 references

9 May 2019

The sonic hedgehog-patched-gli pathway in human development and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

dorsal/ventral pattern formation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

negative regulation of canonical Wnt signaling pathway

1 reference

9 May 2019

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of transcription by RNA polymerase II

IMP

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

9 May 2019

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

digestive tract morphogenesis

1 reference

9 May 2019

The sonic hedgehog-patched-gli pathway in human development and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

prostate gland development

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of cardiac muscle cell proliferation

1 reference

9 May 2019

miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of cell cycle G1/S phase transition

1 reference

9 May 2019

miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

positive regulation of cell population proliferation

1 reference

9 May 2019

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08151

IMP

Gene Atlas image

PBB GE GLI1 206646 at fs.png
732 × 530; 12 KB

0 references

has part(s)

Zinc finger C2H2-type

1 reference

stated in

InterPro Release 71.0