(Q24308749)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

The crosstalk of mTOR/S6K1 and Hedgehog pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

26

Jaffer Ajani

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

25

Huamin Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

27

Mien-Chie Hung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

4

Weiya Xia

1 reference

26 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

5

Julie G Izzo

1 reference

26 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

12

Jung-Mao Hsu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

21

Tsung-Teh Wu

1 reference

26 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

3

Chia-Jui Yen

1 reference

26 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

Yan Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Qingqing Ding

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jing-Yu Lang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Chia-Wei Li

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jennifer L Hsu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Stephanie A Miller

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Xuemei Wang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Longfei Huo

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Adam M Labaff

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Dongping Liu

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Tzu-Hsuan Huang

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Chien-Chen Lai

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Fuu-Jen Tsai

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Wei-Chao Chang

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Chung-Hsuan Chen

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Navtej S Buttar

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Kenneth K Wang

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Yun Wu

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

374-387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

mTOR: from growth signal integration to cancer, diabetes and ageing

26 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Defining the role of mTOR in cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog signaling in animal development: paradigms and principles

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

19 March 2017

Cancer statistics, 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog fights back: mechanisms of acquired resistance against Smoothened antagonists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

The Hedgehog's tale: developing strategies for targeting cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Recent advances in the development of selective, ATP-competitive inhibitors of mTOR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Small-molecule modulators of the Sonic Hedgehog signaling pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Epidemiology of esophageal cancer: Orient to Occident. Effects of chronology, geography and ethnicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Novel targets in esophageal and gastric cancer: beyond antiangiogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

The applicability of mTOR inhibition in solid tumors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog signalling: emerging evidence for non-canonical pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog signaling in development and cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Role and regulation of human tumor suppressor SUFU in Hedgehog signaling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Esophageal cancer: the precursors (Part II).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Molecularly targeted therapy for gastrointestinal cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Inflammation promotes Barrett's metaplasia and cancer: a unique role for TNFalpha.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Control of p70 s6 kinase by kinase activity of FRAP in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3350095

Esophageal cancer: cases and causes (part I)

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22439934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22439934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2011.12.028

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22439934%20AND%20SRC:MED&resulttype=core&format=json