(Q37334261)

English

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy

scientific article published on 21 January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

chemoradiotherapy

0 references

0 references

esophageal cancer

1 reference

based on heuristic

inferred from title

7

object named as

Jaffer A Ajani

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Michelle Hildebrandt

1

object named as

Michelle A T Hildebrandt

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3

object named as

Mien-Chie Hung

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

4

object named as

Julie G Izzo

1 reference

Europe PubMed Central

19 August 2017

PMC publication ID

author name string

Hushan Yang

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Maosheng Huang

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jie Lin

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Xifeng Wu

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

21 January 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Clinical Oncology

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

27

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

857-871

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

1 reference

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9 September 2017

Activation of the serine/threonine protein kinase Akt during the progression of Barrett neoplasia

1 reference

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9 September 2017

Defining the role of mTOR in cancer

1 reference

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9 September 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

A haplotype map of the human genome

1 reference

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9 September 2017

Efficiency and power in genetic association studies

1 reference

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9 September 2017

Activation of AKT kinases in cancer: implications for therapeutic targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line

1 reference

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9 September 2017

Esophageal cancer: preoperative or definitive chemoradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Treatment of localized esophageal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

The biology and clinical relevance of the PTEN tumor suppressor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Controversies in the multimodality management of locally advanced esophageal cancer: evidence-based review of surgery alone and combined-modality therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Cell signaling by receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Mutational analysis of the PTEN/MMAC1 gene in primary oesophageal squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

9 September 2017

Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

14 September 2017

AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

14 September 2017

Akt involvement in paclitaxel chemoresistance of human ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

14 September 2017

An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

14 September 2017

Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

2 September 2018

Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

2 September 2018

Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738430

2 September 2018

Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of multimodal therapy and surgery for esophageal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excellent interobserver agreement on grading the extent of residual carcinoma after preoperative chemoradiation in esophageal and esophagogastric junction carcinoma: a reliable predictor for patient outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of phosphorylated Akt (pAkt) in gastric carcinoma predicts prognosis and efficacy of chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19164214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1200/JCO.2008.17.6297

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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