(Q24311395)

24 June 2017

Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation (English)

1 reference

negative regulation of hh target transcription factor activity

24 June 2017

0 references

1 reference

Gene Ontology release 2020-05-02

1 reference

Gene Ontology release 2020-05-02

11

1 reference

24 June 2017

10

Daniele de Sanctis

0 references

author name string

Amy L Cherry

1

1 reference

24 June 2017

Csaba Finta

2

1 reference

24 June 2017

Mikael Karlström

3

1 reference

24 June 2017

Qianren Jin

4

1 reference

24 June 2017

Thomas Schwend

5

1 reference

24 June 2017

Juan Astorga-Wells

6

1 reference

24 June 2017

Roman A Zubarev

7

1 reference

24 June 2017

Mark Del Campo

8

1 reference

24 June 2017

Angela R Criswell

9

1 reference

24 June 2017

Rune Toftgård

12

1 reference

24 June 2017

language of work or name

English

0 references

publication date

19 November 2013

1 reference

Acta Crystallographica Section D: Biological Crystallography

24 June 2017

1 reference

24 June 2017

69

1 reference

24 June 2017

Pt 12

1 reference

24 June 2017

2563-2579

1 reference

describes a project that uses

24 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3852661/fullTextXML

inferred from PubMed Central ID database lookup

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

19 March 2017

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19 March 2017

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19 March 2017

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A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

19 March 2017

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19 March 2017

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Suppressor of fused regulates Gli activity through a dual binding mechanism

19 March 2017

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19 March 2017

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Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

19 March 2017

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Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

19 March 2017

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Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

19 March 2017

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

19 March 2017

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Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

19 March 2017

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Structure of the human smoothened receptor bound to an antitumour agent

19 March 2017

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An approach to crystallizing proteins by metal-mediated synthetic symmetrization

19 March 2017

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Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats

19 March 2017

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Structure of the Jab1/MPN Domain and Its Implications for Proteasome Function

19 March 2017

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Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis

19 March 2017

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

19 March 2017

1 reference

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NIH Image to ImageJ: 25 years of image analysis

19 March 2017

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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

19 March 2017

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Dali server: conservation mapping in 3D

19 March 2017

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Features and development of Coot

19 March 2017

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19 March 2017

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19 March 2017

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Scaling and assessment of data quality

19 March 2017

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Mechanisms and functions of Hedgehog signalling across the metazoa

19 March 2017

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Protein-binding assays in biological liquids using microscale thermophoresis

19 March 2017

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Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

19 March 2017

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Characterization of the physical interaction of Gli proteins with SUFU proteins

19 March 2017

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Aberrant mobility phenomena of the DNA repair protein XPA

19 March 2017

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Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

19 March 2017

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Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

19 March 2017

1 reference

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Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms

19 March 2017

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Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

19 March 2017

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Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

19 March 2017

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Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

19 March 2017

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New developments in the ATSAS program package for small-angle scattering data analysis

19 March 2017

1 reference

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LigPlot+: multiple ligand-protein interaction diagrams for drug discovery

7 April 2017

1 reference

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Hedgehog: functions and mechanisms

7 April 2017

1 reference

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X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution

7 April 2017

1 reference

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Modulation of allostery by protein intrinsic disorder

7 April 2017

1 reference

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Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma

27 September 2017

1 reference

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Accurate assessment of mass, models and resolution by small-angle scattering

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Loss of SUFU function in familial multiple meningioma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Fragmentation hydrogen exchange mass spectrometry: a review of methodology and applications

27 September 2017

1 reference

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ID29: a high-intensity highly automated ESRF beamline for macromolecular crystallography experiments exploiting anomalous scattering

27 September 2017

1 reference

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Intrinsically disordered proteins: regulation and disease

27 September 2017

1 reference

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Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium

27 September 2017

1 reference

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Interactions between Hedgehog proteins and their binding partners come into view

27 September 2017

1 reference

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Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

27 September 2017

1 reference

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Hedgehog beyond medulloblastoma and basal cell carcinoma

27 September 2017

1 reference

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Hedgehog signaling in development and cancer.

27 September 2017

1 reference

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Role and regulation of human tumor suppressor SUFU in Hedgehog signaling.

27 September 2017

1 reference

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Assessing protein disorder and induced folding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Hedgehog signaling and congenital malformations

27 September 2017

1 reference

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Crystal structures of fusion proteins with large-affinity tags

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Mutations in SUFU predispose to medulloblastoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

STRAP: editor for STRuctural Alignments of Proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Two cases of nevoid basal cell carcinoma syndrome associated with meningioma caused by a PTCH1 or SUFU germline mutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

High frequency of germline SUFU mutations in children with desmoplastic/nodular medulloblastoma younger than 3 years of age.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes

30 May 2018

1 reference

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The ID23-2 structural biology microfocus beamline at the ESRF.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

30 May 2018

1 reference

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PAS domain allostery and light-induced conformational changes in photoactive yellow protein upon I2 intermediate formation, probed with enhanced hydrogen/deuterium exchange mass spectrometry

30 May 2018

1 reference

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Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development

30 May 2018

1 reference

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Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators

30 May 2018

1 reference

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Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium

30 May 2018

1 reference

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Teratogen-mediated inhibition of target tissue response to Shh signaling.

21 January 2018

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DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

21 January 2018

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From proteases to proteomics

21 January 2018

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PRIMUS: a Windows PC-based system for small-angle scattering data analysis

21 January 2018

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The ID23-1 structural biology beamline at the ESRF.

21 January 2018

1 reference

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Identification of a SUFU germline mutation in a family with Gorlin syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

Structure and intrinsic disorder in protein autoinhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

SOPMA: significant improvements in protein secondary structure prediction by consensus prediction from multiple alignments.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3852661

ID14 'Quadriga', a Beamline for Protein Crystallography at the ESRF

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24311597

12 December 2020

inferred from PubMed ID database lookup

xia2: an expert system for macromolecular crystallography data reduction

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

7 January 2021

inferred from DOI database lookup

On the treatment of negative intensity observations

1 reference

https://api.crossref.org/works/10.1107%2FS0907444913028473

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1107/S0907444913028473

1 reference

24 June 2017

0 references

1 reference