(Q55144722)

English

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

scientific article published in July 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand. (English)

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

0 references

author name string

Jong-Sup Bae

1

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

Alireza R Rezaie

2

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

publication date

1 July 2008

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

Thrombosis and Haemostasis

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

100

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

1

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

101-109

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

Dual regulation of endothelial junctional permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Differential expression, time course and distribution of four PARs in rats with endotoxin-induced acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

The cytoprotective protein C pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Multifunctional specificity of the protein C/activated protein C Gla domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Protease-activated receptors in hemostasis, thrombosis and vascular biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Studies on inflammation. 1. The effect of histamine and serotonin on vascular permeability: an electron microscopic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Specificity of coagulation factor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Vascular endothelial cell activation and permeability responses to thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Structure and function of protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Regulation of blood coagulation by the protein C system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

24 June 2018

Activated protein C downregulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

Is APC activation of endothelial cell PAR1 important in severe sepsis?: No.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

PAR1 cleavage and signaling in response to activated protein C and thrombin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562749

13 August 2018

A model for thrombin protection against endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and coagulation: linked processes potentially regulated through a common pathway mediated by protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular events that control the protein C anticoagulant pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of coagulation inhibitors in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18612544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1160/TH08-02-0127

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 June 2018

http://europepmc.org/abstract/PMC/2562749

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