(Q55208509)

25 June 2018

title

Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. (English)

1 reference

25 June 2018

author

Matteo Pellegrini

16

1 reference

25 June 2018

author name string

Minori Ohashi

1

1 reference

25 June 2018

Elena Korsakova

2

1 reference

25 June 2018

Denise Allen

3

1 reference

25 June 2018

Peiyee Lee

4

1 reference

25 June 2018

Kai Fu

5

1 reference

25 June 2018

Benni S Vargas

6

1 reference

25 June 2018

Jessica Cinkornpumin

7

1 reference

25 June 2018

Carlos Salas

8

1 reference

25 June 2018

Jenny C Park

9

1 reference

25 June 2018

Igal Germanguz

10

1 reference

25 June 2018

Justin Langerman

11

1 reference

25 June 2018

Contantinos Chronis

12

1 reference

25 June 2018

Edward Kuoy

13

1 reference

25 June 2018

Stephen Tran

14

1 reference

25 June 2018

Xinshu Xiao

15

1 reference

25 June 2018

Kathrin Plath

17

1 reference

25 June 2018

William E Lowry

18

1 reference

25 June 2018

publication date

1 May 2018

1 reference

25 June 2018

published in

Stem Cell Reports

1 reference

25 June 2018

volume

10

1 reference

25 June 2018

issue

5

1 reference

25 June 2018

page(s)

1453-1463

1 reference

25 June 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5995366/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

let-7 miRNAs can act through notch to regulate human gliogenesis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Are there roles for brain cell senescence in aging and neurodegenerative disorders?

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Erosion of dosage compensation impacts human iPSC disease modeling

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Defining the nature of human pluripotent stem cell progeny

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Female human iPSCs retain an inactive X chromosome

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Telomere dynamics in human cells reprogrammed to pluripotency.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Generation of human induced pluripotent stem cells from dermal fibroblasts

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

A global map of p53 transcription-factor binding sites in the human genome

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic Target.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Rett Syndrome and the Ongoing Legacy of Close Clinical Observation

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Developmental abnormalities of cortical interneurons precede symptoms onset in a mouse model of Rett syndrome.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Methods of cellular senescence induction using oxidative stress

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

The methyl-CpG-binding protein MeCP2 and neurological disease

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5995366

Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs

13 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29742391

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEMCR.2018.04.001

1 reference

25 June 2018

PMC publication ID

5995366

1 reference

25 June 2018

PubMed publication ID

29742391

1 reference

25 June 2018