(Q55239901)

28 June 2018

title

Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling. (English)

1 reference

28 June 2018

author name string

Baker BM

1

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28 June 2018

Gagnon SJ

2

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28 June 2018

Biddison WE

3

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28 June 2018

Wiley DC

4

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28 June 2018

language of work or name

English

0 references

publication date

1 October 2000

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28 June 2018

published in

Immunity

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28 June 2018

volume

13

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28 June 2018

issue

4

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28 June 2018

page(s)

475-484

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28 June 2018

T-cell-receptor affinity and thymocyte positive selection

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Structural, biochemical, and biophysical studies of HLA-A2/altered peptide ligands binding to viral-peptide-specific human T-cell receptors

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Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit binding

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The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

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A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

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The Entropic Cost of Bound Water in Crystals and Biomolecules

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Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect

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Evidence for multivalent structure of T-cell antigen receptor complex

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Multivalent structure of an alphabetaT cell receptor

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HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

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Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

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Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

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Ligands for the T-cell receptor: hard times for avidity models

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Cross-linking and conformational change in T-cell receptors: role in activation and in repertoire selection

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7 January 2021

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

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7 January 2021

The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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SURFNET: a program for visualizing molecular surfaces, cavities, and intermolecular interactions

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A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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7 January 2021

The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

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7 January 2021

Kinetic proofreading in T-cell receptor signal transduction

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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Improving biosensor analysis

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Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

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7 January 2021

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7 January 2021

Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model

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7 January 2021

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

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7 January 2021

Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

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7 January 2021

Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type 1 (HTLV-1) Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion

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7 January 2021

Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59

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7 January 2021

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Identifiers

DOI

1 reference

28 June 2018

1 reference

28 June 2018