Wikidata

(Q5530676)

English

Geminin DNA replication inhibitor

mammalian protein found in Homo sapiens

  • GMNN
  • geminin
  • uniprot:O75496
In more languages

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex
GOA
curator
UniProt
UniProt protein ID
O75496
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
A WD-repeat protein stabilizes ORC binding to chromatin
GOA
curator
UniProt
UniProt protein ID
O75496
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Self-assembling protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
retrieved
8 April 2019
stated in
JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE GMNN 218350 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q5530676&oldid=2022908072"