(Q24301413)

Multiciliate differentiation and DNA synthesis associated cell cycle protein

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Anastassis Perrakis

8

0 references

Stavros Taraviras

object named as

Stavros Taraviras

9

0 references

Zoi Lygerou

10

object named as

Zoi Lygerou

0 references

author name string

Dafni-Eleutheria Pefani

1

0 references

Maria Dimaki

2

0 references

Magda Spella

3

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Nickolas Karantzelis

4

0 references

Eirini Mitsiki

5

0 references

Christina Kyrousi

6

0 references

Ioanna-Eleni Symeonidou

Journal of Biological Chemistry

7

0 references

language of work or name

English

0 references

publication date

1 July 2011

0 references

published in

0 references

volume

286

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issue

26

0 references

page(s)

23234-46

0 references

cites work

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Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin

19 March 2017

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Geminin regulates neuronal differentiation by antagonizing Brg1 activity

19 March 2017

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Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

19 March 2017

1 reference

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Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

19 March 2017

1 reference

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Loss of Geminin induces rereplication in the presence of functional p53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Direct interaction of geminin and Six3 in eye development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

19 March 2017

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1

19 March 2017

1 reference

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The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin, an inhibitor of DNA replication, is degraded during mitosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development

19 March 2017

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Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

19 March 2017

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Clustal W and Clustal X version 2.0

19 March 2017

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Inference of macromolecular assemblies from crystalline state

19 March 2017

1 reference

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Predicting coiled coils from protein sequences

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin in embryonic development: coordinating transcription and the cell cycle during differentiation

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

A mechanism regulating the onset of Sox2 expression in the embryonic neural plate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

The anaphase-promoting complex/cyclosome: APC/C.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin's double life: chromatin connections that regulate transcription at the transition from proliferation to differentiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin coordinates cell cycle and developmental control

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Gene2EST: a BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

Cell type-specific responses of human cells to inhibition of replication licensing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123090

A BAC-based physical map of the major autosomes of Drosophila melanogaster.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Crystal structure of the coiled-coil dimerization motif of geminin: structural and functional insights on DNA replication regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Subcellular translocation signals regulate Geminin activity during embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

A chromatin link that couples cell division to root epidermis patterning in Arabidopsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

A green GEM: intriguing analogies with animal geminin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207688

Cell cycle. License withheld--geminin blocks DNA replication

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21543332