(Q55383295)

5 July 2018

title

Frequent epigenetic silencing of the p16 gene in non-small cell lung cancers of tobacco smokers. (English)

1 reference

5 July 2018

author name string

Naoki Yanagawa

1

1 reference

5 July 2018

Gen Tamura

2

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5 July 2018

Hiroyuki Oizumi

3

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5 July 2018

Nobumasa Takahashi

4

1 reference

5 July 2018

Yasuhisa Shimazaki

5

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5 July 2018

Teiichi Motoyama

6

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5 July 2018

publication date

1 October 2002

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5 July 2018

number of pages

7

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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5 July 2018

volume

93

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5 July 2018

page(s)

1107-1113

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5 July 2018

issue

10

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5 July 2018

Molecular and genetic aspects of lung cancer

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Association between cigarette smoking and FHIT gene alterations in lung cancer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Frequent aberrant methylation of p16INK4a in primary rat lung tumors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

A cell cycle regulator potentially involved in genesis of many tumor types

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

G1 phase progression: cycling on cue

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

The retinoblastoma protein and cell cycle control

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Aberrant promoter methylation of multiple genes in non-small cell lung cancers.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: relationship with tumor growth parameters and ploidy status.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Implications and prognostic value of K-ras mutation for early-stage lung cancer in women

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Correlation between methylation status of the p16/CDKN2 gene and the expression of p16 and Rb proteins in primary non-small cell lung cancers.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Rb and p16INK4a expression in resected non-small cell lung tumors.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2, and p18 genes in primary and metastatic lung cancer

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Loss of heterozygosity on the short arm of chromosome 9 without p16 gene mutation in gastric carcinomas.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926878

Cigarette smoke induces DNA single-strand breaks in human cells

2 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2002.TB01212.X

Alterations of CDKN2 (p16) in non-small cell lung cancer

21 January 2018

1 reference

12 December 2020

Meta-analyses of p53 tumor suppressor gene alterations and clinicopathological features in resected lung cancers

1 reference

12 December 2020

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

12 December 2020

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

1 reference

12 December 2020

Prognostic value of p53 in non-small cell lung cancer: Relationship with proliferating cell nuclear antigen and cigarette smoking

1 reference

12 December 2020

Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization

1 reference

12 December 2020

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

12 December 2020

DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: its association with smoking history

1 reference

12 December 2020

High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma

1 reference

12 December 2020

Mechanisms of p16INK4A inactivation in non small-cell lung cancers

1 reference

12 December 2020

10.1111/J.1349-7006.2002.TB01212.X

Identifiers

DOI

1 reference

5 July 2018

PMCID

5926878

1 reference

5 July 2018

PubMed ID

12417040

1 reference

5 July 2018