(Q55548365)

http://europepmc.org/abstract/PMC/6026004

15 July 2018

title

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies. (English)

1 reference

http://europepmc.org/abstract/PMC/6026004

15 July 2018

author

Yackov Berkun

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Hanna Kim

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Laura Failla

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Gina A Montealegre Sanchez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Adam Reinhardt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Suzanne Ramsey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Helmut Wittkowski

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Philip J Hashkes

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Susanne Schalm

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Sara Murias

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jason A Dare

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Diane Brown

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Deborah L Stone

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Ling Gao

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Thomas Klausmeier

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dirk Foell

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Adriana A de Jesus

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dawn C Chapelle

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Samantha Dill

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Robert A Colbert

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Bahar Kost

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Michelle O'Brien

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

James C Reynolds

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Les R Folio

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Katherine R Calvo

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Scott M Paul

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Nargues Weir

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alessandra Brofferio

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Ariane Soldatos

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Angelique Biancotto

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Edward W Cowen

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

John J Digiovanna

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Massimo Gadina

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Andrew J Lipton

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Colleen Hadigan

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Steven M Holland

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Joseph Fontana

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Ahmad S Alawad

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Rebecca J Brown

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kristina I Rother

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Theo Heller

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kristina M Brooks

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Parag Kumar

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Stephen R Brooks

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Meryl Waldman

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Harsharan K Singh

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Volker Nickeleit

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Maria Silk

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Apurva Prakash

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jonathan M Janes

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Seza Ozen

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Paul G Wakim

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Paul A Brogan

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

William L Macias

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Raphaela Goldbach-Mansky

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

11 June 2018

1 reference

http://europepmc.org/abstract/PMC/6026004

15 July 2018

published in

Journal of Clinical Investigation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

3041-3052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis

10 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling

27 July 2018

1 reference

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Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Baricitinib in Patients with Refractory Rheumatoid Arthritis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Parsing the Interferon Transcriptional Network and Its Disease Associations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Epigenetic regulation of macrophage polarization and function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver

27 July 2018

1 reference

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Mutations in proteasome subunit β type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity.

27 July 2018

1 reference

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A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

PSMB8 encoding the β5i proteasome subunit is mutated in joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced lipodystrophy syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Monocyte chemoattractant protein-1 expression is enhanced by granulocyte-macrophage colony-stimulating factor via Jak2-Stat5 signaling and inhibited by atorvastatin in human monocytic U937 cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Discovery and epidemiology of the human polyomaviruses BK virus (BKV) and JC virus (JCV).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

The metabolic syndrome and concentrations of C-reactive protein among U.S. youth

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Jaks and STATs: biological implications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Development of a Validated Interferon Score Using NanoString Technology.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Familial chilblain lupus due to a gain-of-function mutation in STING.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Activated STING in a vascular and pulmonary syndrome

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

The human polyomavirus BK (BKPyV): virological background and clinical implications

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

GM-CSF priming of human monocytes is dependent on ERK1/2 activation

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Prevalence and patterns of polyomavirus urinary excretion in immunocompetent adults and children.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Mixed Models for Assessing Correlation in the Presence of Replication

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Gigantism in mice lacking suppressor of cytokine signalling-2

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Simple proton spectroscopic imaging

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Type I interferonopathies: a novel set of inborn errors of immunity

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

Intracerebral large artery disease in Aicardi-Goutières syndrome implicates SAMHD1 in vascular homeostasis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6026004

30 November 2018

Identifiers

DOI

10.1172/JCI98814

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29649002%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference