(Q55712500)

22 July 2018

title

Dependence of acute myeloid leukemia on adhesion within the bone marrow microenvironment. (English)

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22 July 2018

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acute myeloid leukemia

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Pamela S Becker

1

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22 July 2018

language of work or name

English

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publication date

4 January 2012

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22 July 2018

The Scientific World Journal

published in

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22 July 2018

volume

2012

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22 July 2018

page(s)

856467

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22 July 2018

Creative Commons Attribution 3.0 Unported

copyright license

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group

27 July 2018

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Environment-mediated drug resistance: a major contributor to minimal residual disease

27 July 2018

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Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells

27 July 2018

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27 July 2018

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

27 July 2018

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Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia

27 July 2018

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Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia

27 July 2018

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CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth

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High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event

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Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists

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12 August 2018

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Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

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12 August 2018

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Beta1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells.

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Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

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Targeting of CD44 eradicates human acute myeloid leukemic stem cells

12 August 2018

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CXCR4 is a prognostic marker in acute myelogenous leukemia.

12 August 2018

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A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia.

12 August 2018

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CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice

12 August 2018

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CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow

12 August 2018

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CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).

12 August 2018

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Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

12 August 2018

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Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins

12 August 2018

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Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells

12 August 2018

1 reference

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Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5).

12 August 2018

1 reference

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Levels of circulating endothelial adhesion molecules (sE-selectin and sVCAM-1) in adult patients with acute leukemia.

12 August 2018

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Endothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination

12 August 2018

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12 December 2020

Migratory behavior of leukemic cells from acute myeloid leukemia patients

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12 December 2020

Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells

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12 December 2020

Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

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12 December 2020

The relationship between bone, hemopoietic stem cells, and vasculature

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12 December 2020

Identifiers

DOI

10.1100/2012/856467

1 reference

22 July 2018

PMC publication ID

3259714

1 reference

22 July 2018

PubMed publication ID

22346731

1 reference

22 July 2018