(Q56352603)

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Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29909069%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29909069%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

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Plasmodium vivax

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Plasmodium falciparum

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Plasmodium vivax malaria

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Alejandro Llanos Cuentas

1

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31 March 2020

David A. Fidock

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31 March 2020

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31 March 2020

Margaret A. Phillips

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Margaret A Phillips

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31 March 2020

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Martin Casapia

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31 March 2020

Raúl Chuquiyauri

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31 March 2020

Juan-Carlos Hinojosa

4

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31 March 2020

Nicola Kerr

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31 March 2020

Maria Rosario

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31 March 2020

Stephen Toovey

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31 March 2020

Robert H Arch

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31 March 2020

Felix D Rozenberg

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31 March 2020

Jade Bath

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31 March 2020

Caroline L Ng

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31 March 2020

Annie N Cowell

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31 March 2020

Elizabeth A Winzeler

14

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31 March 2020

Mark Baker

16

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31 March 2020

Jörg J Möhrle

17

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31 March 2020

Nathalie Gobeau

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31 March 2020

Nada Araeipour

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31 March 2020

Nicole Andenmatten

21

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31 March 2020

Thomas Rückle

22

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31 March 2020

Rob Hooft van Huijsduijnen

18

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31 March 2020

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13 June 2018

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31 March 2020

Lancet Infectious Diseases

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31 March 2020

18

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31 March 2020

8

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31 March 2020

874-883

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31 March 2020

Drug resistance in Plasmodium.

1 reference

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29 September 2018

Assessing drug efficacy against Plasmodium falciparum liver stages in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

A randomized trial of the prophylactic activity of DSM265 against pre-erythrocytic Plasmodium falciparum controlled human malaria infection by mosquito bites and direct venous inoculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

New developments in anti-malarial target candidate and product profiles

1 reference

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29 September 2018

A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

1 reference

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29 September 2018

Malaria medicines: a glass half full?

1 reference

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29 September 2018

Developing regional weight-for-age growth references for malaria-endemic countries to optimize age-based dosing of antimalarials

1 reference

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29 September 2018

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

1 reference

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29 September 2018

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

Malaria: uncomplicated, caused by Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6060173

29 September 2018

The International Conference on Harmonization Good Clinical Practice guideline.

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29 September 2018

Assessment of the pharmacodynamic properties of antimalarial drugs in vivo

2 references

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29 September 2018

https://api.crossref.org/works/10.1016%2FS1473-3099%2818%2930309-8

7 January 2021

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Cardiac involvement during and after malaria

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29 September 2018

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10.1016/S1473-3099(18)30309-8

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Europe PubMed Central

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31 March 2020

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31 March 2020

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31 March 2020

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