(Q56387142)

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Facile air oxidation of the conjugate base of rofecoxib (Vioxx™), a possible contributor to chronic human toxicity

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Facile air oxidation of the conjugate base of rofecoxib (Vioxx™), a possible contributor to chronic human toxicity (English)

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2

E.J. Corey

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author name string

Leleti Rajender Reddy

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1

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publication date

February 2005

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published in

Tetrahedron Letters

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46

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927-929

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6

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cites work

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The coxibs, selective inhibitors of cyclooxygenase-2.

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Cyclooxygenase 2: a molecular target for cancer prevention and treatment

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Coxibs and cardiovascular disease

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Failing the public health--rofecoxib, Merck, and the FDA.

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Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx)

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Role of prostacyclin in the cardiovascular response to thromboxane A2

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Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

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Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

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Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TETLET.2004.12.055

The disposition and metabolism of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in human subjects

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Isolation and characterisation of process-related impurities in rofecoxib

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10.1016/J.TETLET.2004.12.055

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(Q56387142)

Facile air oxidation of the conjugate base of rofecoxib (Vioxx™), a possible contributor to chronic human toxicity

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