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(Q56564080)
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erythrocyte binding antigen-175
protein found in Plasmodium falciparum 3D7, encoded by EBA175
PF07_0128
MAL7P1.176
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Statements
instance of
protein
1 reference
stated in
GeneDB
retrieved
11 September 2018
subclass of
protein
1 reference
stated in
GeneDB
retrieved
11 September 2018
part of
Duffy-antigen binding protein family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IBE8
Erythrocyte binding antigen 175, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Plasmodium falciparum 3D7
1 reference
stated in
GeneDB
retrieved
25 February 2019
encoded by
EBA175
1 reference
stated in
GeneDB
retrieved
11 September 2018
molecular function
host cell surface receptor binding
UniProt protein ID
P02724
determination method
IPI
point in time
19 September 2013
2 references
curator
GeneDB
stated in
Biochemical analysis of the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction: implications for vaccine design
retrieved
26 June 2019
curator
GeneDB
stated in
A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin A
retrieved
26 June 2019
heparin binding
determination method
IDA
point in time
12 November 2013
1 reference
curator
GeneDB
stated in
Analyses of interactions between heparin and the apical surface proteins of Plasmodium falciparum
retrieved
26 June 2019
cell component
microneme
determination method
IDA
point in time
27 December 2012
2 references
curator
GeneDB
stated in
A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites
retrieved
26 June 2019
curator
GeneDB
stated in
The upstream sequence segment of the C-terminal cysteine-rich domain is required for microneme trafficking of Plasmodium falciparum erythrocyte binding antigen 175.
retrieved
26 June 2019
integral component of membrane
InterPro ID
IPR008602
determination method
IEA
point in time
1 September 2020
1 reference
curator
GeneDB
retrieved
3 October 2020
reference URL
https://github.com/geneontology/go-site/blob/master/metadata/gorefs/goref-0000002.md
extracellular vesicle
determination method
HDA
point in time
7 February 2019
1 reference
curator
GeneDB
stated in
Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.
retrieved
26 June 2019
biological process
modulation by symbiont of host receptor-mediated signal transduction
determination method
IMP
point in time
23 February 2017
1 reference
curator
GeneDB
stated in
Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
retrieved
26 June 2019
entry into host
determination method
IMP
point in time
6 April 2017
1 reference
curator
GeneDB
stated in
Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion
retrieved
3 April 2020
described by source
Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum.
determination method
IDA
subject named as
erythrocyte binding antigen-175
1 reference
curator
GeneDB
retrieved
13 March 2019
has part(s)
Erythrocyte binding antigen 175, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IBE8
Identifiers
UniProt protein ID
Q8IBE8
1 reference
stated in
GeneDB
retrieved
11 September 2018
GeneDB ID
PF3D7_0731500.1
1 reference
stated in
GeneDB
retrieved
11 September 2018
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