(Q56777088)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

29 December 2019

main subject

0 references

author

Tomohiro Kabuta

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Yasuyuki Suzuki

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Keiji Wada

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

18 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

30524-30533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

Unraveling the mechanisms involved in motor neuron degeneration in ALS

29 December 2019

cites work

1 reference

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

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Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

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Protein degradation and protection against misfolded or damaged proteins

21 January 2018

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Autophagy: in sickness and in health

21 January 2018

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Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

21 January 2018

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Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

21 January 2018

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NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

21 January 2018

1 reference

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Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

21 January 2018

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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

21 January 2018

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Proteasomal degradation of mutant superoxide dismutases linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

21 January 2018

1 reference

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Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

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Insulin receptor substrate-3 functions as transcriptional activator in the nucleus

21 January 2018

1 reference

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Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

1 reference

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Separation of cathepsin A-like enzyme and the proteasome: evidence that lactacystin/beta-lactone is not a specific inhibitor of the proteasome

21 January 2018

1 reference

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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

21 January 2018

1 reference

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Recent advances in the identification and development of 20S proteasome inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Autophagy regulates the processing of amino terminal huntingtin fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

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Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

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Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS.

21 January 2018

1 reference

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New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes.

21 January 2018

1 reference

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

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Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates.

21 January 2018

1 reference

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No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

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The differential degradation of two cytosolic proteins as a tool to monitor autophagy in hepatocytes by immunocytochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603337200

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

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Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M603337200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920710%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference