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New developments in anti-HIV chemotherapy
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
New developments in anti-HIV chemotherapy
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
chemotherapy
1 reference
based on heuristic
inferred from title
HIV
0 references
author
Erik De Clercq
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
publication date
1 July 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
number of pages
18
1 reference
based on heuristic
inferred from page(s)
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
1587
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
2-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
258-275
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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Crossref
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7 January 2021
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Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells
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Crossref
reference URL
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7 January 2021
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Correlation of anti-HIV activity with anion spacing in a series of cosalane analogues with extended polycarboxylate pharmacophores.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sulfated Polysaccharides Extracted from Sea Algae as Potential Antiviral Drugs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
A general model for the surface glycoproteins of HIV and other retroviruses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Highly sulfated forms of heparin sulfate are involved in japanese encephalitis virus infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyanions--a lost chance in the fight against HIV and other virus diseases?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(sodium 4-styrene sulfonate): an effective candidate topical antimicrobial for the prevention of sexually transmitted diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The LD78beta isoform of MIP-1alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The LD78beta isoform of MIP-1alpha is the most potent CC-chemokine in inhibiting CCR5-dependent human immunodeficiency virus type 1 replication in human macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor Fusin/CXCR-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of chemokine receptors in breast cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 entry inhibitors in the side pocket
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity to a nonpeptidic compound (RPR103611) blocking human immunodeficiency virus type 1 Env-mediated fusion depends on sequence and accessibility of the gp41 loop region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ADA, a potential anti-HIV drug
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple effects of an anti-human immunodeficiency virus nucleocapsid inhibitor on virus morphology and replication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I/II dose escalation and randomized withdrawal study with add-on azodicarbonamide in patients failing on current antiretroviral therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Azodicarbonamide inhibits T-cell responses in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II placebo-controlled trial of fozivudine tidoxil for HIV infection: pharmacokinetics, tolerability, and efficacy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lasting effects of transient postinoculation tenofovir [9-R-(2-Phosphonomethoxypropyl)adenine] treatment on SHIV(KU2) infection of rhesus macaques.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro anti-human immunodeficiency virus activities of Z- and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
S-1153 inhibits replication of known drug-resistant strains of human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrido [1,2a] indole derivatives identified as novel non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel modifications in the alkenyldiarylmethane (ADAM) series of non-nucleoside reverse transcriptase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SJ-3366, a unique and highly potent nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1) that also inhibits HIV-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and pharmacokinetics of single doses of (+)-calanolide a, a novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy, human immunodeficiency virus-negative human subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retroviral integrase inhibitors year 2000: update and perspectives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiazolothiazepine inhibitors of HIV-1 integrase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-chicoric acid, an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase, improves on the in vitro anti-HIV-1 effect of Zidovudine plus a protease inhibitor (AG1350).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human immunodeficiency virus type-1 integrase by curcumin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Curcumin Analogs with Altered Potencies against HIV-1 Integrase as Probes for Biochemical Mechanisms of Drug Action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus gene regulation as a target for antiviral chemotherapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1-trans-activating (Tat) protein: both a target and a tool in therapeutic approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent and selective inhibition of human immunodeficiency virus type 1 transcription by piperazinyloxoquinoline derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of acute-, latent-, and chronic-phase human immunodeficiency virus type 1 (HIV-1) replication by a bistriazoloacridone analog that selectively inhibits HIV-1 transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of HIV-1 transcription and virus replication using soluble Tat peptide analogs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of HIV-1 replication by a Tat RNA-binding domain peptide analog.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent developments in HIV protease inhibitor therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Convergent, Scalable Synthesis of HIV Protease Inhibitor PNU-140690
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class∇
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Susceptibility to PNU-140690 (Tipranavir) of human immunodeficiency virus type 1 isolates derived from patients with multidrug resistance to other protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2802%2900089-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0925-4439(02)00089-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
12084468
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12084468
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084468%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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