(Q56798186)

1

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Robert T. Elder

2

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Kefeng Qin

3

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Hyeon Ung Park

4

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Dong Liang

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

8 January 2007

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published in

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volume

282

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issue

10

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page(s)

7287-7298

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cites work

Regulation of DNA replication by ATR: signaling in response to DNA intermediates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

The when and wheres of CDC25 phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Checking on DNA damage in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Initiating cellular stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Protein phosphatase 5 is required for ATR-mediated checkpoint activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

TopBP1 activates the ATR-ATRIP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Increased levels of Wee-1 kinase in G(2) are necessary for Vpr- and gamma irradiation-induced G(2) arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

H2AX: the histone guardian of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Type 2A protein phosphatase, the complex regulator of numerous signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Protein phosphatase 2A: a panoply of enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

PP2A: the expected tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Molecular cloning and sequence analysis of the catalytic subunit of bovine type 2A protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Genetic studies with the fission yeast Schizosaccharomyces pombe suggest involvement of wee1, ppa2, and rad24 in induction of cell cycle arrest by human immunodeficiency virus type 1 Vpr

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

A novel inducible expression system to study transdominant mutants of HIV-1 Vpr.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Specific gene inhibition by adenovirus-mediated expression of small interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

The use of nocodazole in cell cycle analysis and parasite purification from Theileria parva-infected B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human parvovirus B19 induces cell cycle arrest at G(2) phase with accumulation of mitotic cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Human claspin is required for replication checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Claspin, a regulator of Chk1 in DNA replication stress pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Chk1 is required to maintain claspin stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Baculovirus expression, purification, and characterization of human protein phosphatase 2A catalytic subunits alpha and beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

The formation and activity of PP2A holoenzymes do not depend on the isoform of the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200

Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607951200