(Q56858782)

English

Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9606151)

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8 July 2022

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

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8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9606151

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8 July 2022

Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane]

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1 reference

8 July 2022

Bruton's tyrosine kinase

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8 July 2022

NCK adaptor protein 1

1

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8 July 2022

Phospholipase C gamma 2

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8 July 2022

Vav guanine nucleotide exchange factor 1

1

1 reference

8 July 2022

Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane]

1

1 reference

8 July 2022

1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)

2

1 reference

8 July 2022

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

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8 July 2022

BLNK: a central linker protein in B cell activation

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8 July 2022

BLNK mediates Syk-dependent Btk activation

1 reference

8 July 2022

BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins

1 reference

8 July 2022

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

1 reference

8 July 2022

Identification of the SH2 domain binding protein of Bruton's tyrosine kinase as BLNK--functional significance of Btk-SH2 domain in B-cell antigen receptor-coupled calcium signaling

1 reference

8 July 2022

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q56858782)

Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1

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