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Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans

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Cutting edge: CTLA-4 on effector T cells inhibits in trans

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Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans (English)

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Cutting edge: CTLA-4 on effector T cells inhibits in trans (English)

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2

James P Allison

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E. Corse

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1

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J. P. Allison

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2

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Emily Corse

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1

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language of work or name

English

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publication date

2 July 2012

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1 August 2012

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published in

Journal of Immunology

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volume

189

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issue

3

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page(s)

1123-1127

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1123-7

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cites work

CTLA-4 can function as a negative regulator of T cell activation

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/1074-7613(94)90071-X

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Thymocyte development is normal in CTLA-4-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

CTLA-4 control over Foxp3+ regulatory T cell function

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Lack of intrinsic CTLA-4 expression has minimal effect on regulation of antiviral T-cell immunity.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Ligand recognition by alpha beta T cell receptors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

CD28 and CTLA-4 coreceptor expression and signal transduction

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Enhancement of antitumor immunity by CTLA-4 blockade

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Attenuated T cell responses to a high-potency ligand in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

CTLA-4: not all costimulation is stimulatory

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.1200695

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DOI

10.4049/JIMMUNOL.1200695

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PubMed publication ID

22753941

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(Q56888747)

Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans

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